The clinical protocol for this study EPIC002 has been previously described[38 (link),39 (link)]. The study is registered on clinicaltrials.gov as NCT03246230 . In brief, mothers-infant pairs were consented and enrolled at time of delivery at the Medical Research Council (MRC) Unit at the London School of Hygiene and Tropical Medicine in The Gambia. HIV- and Hepatitis B-negative mothers 18 years or older, were enrolled. Infants were enrolled if >36 weeks of gestational age (as determined by Ballard scoring), with Apgar scores >8 at 5 min and birth weight >2.5 kg. Peripheral blood samples (max volume 2 ml) were collected from infants using sterile sodium heparin tubes (Becton Dickinson). Four time points were collected: Visit 1 (V1), was collected within the first 24 h of life (Day of Life (DOL)0); while the Visit 2 (V2) sample was collected at either DOL1, or DOL3, or DOL7. Plasma samples were processed for analysis as previously published [40 (link)]. All plasma samples were stored at −80 ℃ until use. Local and International IRB committees approved all protocols utilized.
Sterile sodium heparin tubes
Manufactured by BD
Sterile sodium heparin tubes are laboratory containers used for the collection and storage of blood samples. They contain a sodium heparin anticoagulant, which prevents the blood from clotting during the collection and handling process. These tubes are designed to maintain the integrity of the blood sample for various laboratory analyses.
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Lab products found in correlation
2 protocols using sterile sodium heparin tubes
1
Gambian Newborn Immune Profiling
2
Gambian Newborn Immune Profiling
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The clinical protocol for this study EPIC002 has been previously described[38 (link),39 (link)]. The study is registered on clinicaltrials.gov as NCT03246230 . In brief, mothers-infant pairs were consented and enrolled at time of delivery at the Medical Research Council (MRC) Unit at the London School of Hygiene and Tropical Medicine in The Gambia. HIV- and Hepatitis B-negative mothers 18 years or older, were enrolled. Infants were enrolled if >36 weeks of gestational age (as determined by Ballard scoring), with Apgar scores >8 at 5 min and birth weight >2.5 kg. Peripheral blood samples (max volume 2 ml) were collected from infants using sterile sodium heparin tubes (Becton Dickinson). Four time points were collected: Visit 1 (V1), was collected within the first 24 h of life (Day of Life (DOL)0); while the Visit 2 (V2) sample was collected at either DOL1, or DOL3, or DOL7. Plasma samples were processed for analysis as previously published [40 (link)]. All plasma samples were stored at −80 ℃ until use. Local and International IRB committees approved all protocols utilized.
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