All patients underwent contrast-enhanced CT scanning prior to radiation treatment on a Philips Brilliance iCT scanner (Philips Healthcare, Best, The Netherlands) using a standardized protocol for HNC patients. The imaging was performed in treatment position in a radiotherapy immobilization mask. Scanning parameters included slice thickness 1 mm with a 2 mm interslice gap.
Brilliance ict scanner
Manufactured by Philips
Sourced in Germany, United States
The Philips Brilliance iCT scanner is a computed tomography (CT) system designed for diagnostic imaging. It utilizes advanced imaging technology to generate high-quality, detailed cross-sectional images of the body. The core function of the Brilliance iCT scanner is to provide healthcare professionals with the necessary imaging data to support clinical decision-making.
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Lab products found in correlation
11 protocols using brilliance ict scanner
1
Contrast-Enhanced CT Imaging for HNC
2
Multi-phase CT Imaging for Tumor Assessment
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All imaging was performed with the patient positioned in a radiotherapy mask using a Philips Brilliance iCT scanner (Philips Healthcare, Best, the Netherlands). The imaging protocol consisted of non‐contrast CT (NCCT), DCECT and CECT.
The NCCT was acquired using 128x0.625 mm collimation, 80 kVp, 100 mAs, a rotation time of 0.75s, 220 mm FOV, and a 512x512 matrix.
The DCECT slab was centered to the level of the tumor as identified on the NCCT. For the acquisition three consecutive series were made: the first series with 20 frames each 3 seconds, the second series with 10 frames every 6 seconds, and the third series with 10 frames every 20 seconds. The first series were acquired without post‐injection delay during injection of 50 ml non‐ionic iodine contrast agent (Ultravist 300, Bayer‐Schering Pharma AG, Berlin, Germany) into the antecubital vein at a rate of 5 ml/s, followed by a 40‐ml saline flush. The first frames were therefore unenhanced. Scans were acquired in axial mode using 128x0.625 mm collimation, 120 kVp, 200 mAs, a rotation time of 0.4s, 180 mm FOV, and a 512x512 matrix.
Subsequently the CECT images were acquired 65 seconds after injection of another 90 ml of non‐ionic iodine contrast agent at a rate of 5 ml/s followed by a 30‐ml saline flush using 128x0.625 mm collimation, 120 kVp, 150 mAs, a rotation time of 0.4s, 220 mm FOV, and a 512x512 matrix.
The NCCT was acquired using 128x0.625 mm collimation, 80 kVp, 100 mAs, a rotation time of 0.75s, 220 mm FOV, and a 512x512 matrix.
The DCECT slab was centered to the level of the tumor as identified on the NCCT. For the acquisition three consecutive series were made: the first series with 20 frames each 3 seconds, the second series with 10 frames every 6 seconds, and the third series with 10 frames every 20 seconds. The first series were acquired without post‐injection delay during injection of 50 ml non‐ionic iodine contrast agent (Ultravist 300, Bayer‐Schering Pharma AG, Berlin, Germany) into the antecubital vein at a rate of 5 ml/s, followed by a 40‐ml saline flush. The first frames were therefore unenhanced. Scans were acquired in axial mode using 128x0.625 mm collimation, 120 kVp, 200 mAs, a rotation time of 0.4s, 180 mm FOV, and a 512x512 matrix.
Subsequently the CECT images were acquired 65 seconds after injection of another 90 ml of non‐ionic iodine contrast agent at a rate of 5 ml/s followed by a 30‐ml saline flush using 128x0.625 mm collimation, 120 kVp, 150 mAs, a rotation time of 0.4s, 220 mm FOV, and a 512x512 matrix.
3
CTP for Acute Ischemic Stroke Assessment
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CTP was performed on admission before possible thrombolytic treatment. All included scans were acquired on a 256-slice Philips Brilliance iCT scanner (Philips Healthcare, Best, The Netherlands) at 80 kVp and 150 mAs/rotation. The scans had a total acquisition time of at least 210 seconds, divided into 25 frames with an approximately 2 second interval, a 15 second pause, and 6 frames with an approximately 30 second interval, resulting in an effective radiation dose of 3.3 mSv. At initiation of scanning, 40 mL of iopromide contrast agent (PubChem ID: 3736, Ultravist 300, Bayer HealthCare, Berlin, Germany) was injected intravenously at a rate of 6 mL/s, followed by a 40 mL saline flush.
The 0.8 mm thin slices, with a field-of view of 20 cm × 20 cm, were reconstructed in a 512 × 512 matrix using filtered backprojection. The reconstructed scans had an axial coverage of 52.0 to 64.8 mm from at least the level of the basal ganglia to the lateral ventricles to be able to assess ASPECTS levels 1 and 2 [23 (link)], resulting in 65 to 81 reconstructed slices.
The 0.8 mm thin slices, with a field-of view of 20 cm × 20 cm, were reconstructed in a 512 × 512 matrix using filtered backprojection. The reconstructed scans had an axial coverage of 52.0 to 64.8 mm from at least the level of the basal ganglia to the lateral ventricles to be able to assess ASPECTS levels 1 and 2 [23 (link)], resulting in 65 to 81 reconstructed slices.
4
Quantifying Arterial Stenosis with CT Angiography
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Pre-procedural CT angiography was performed from the diaphragm to the foot arches with image slice thickness of 1 mm, using a 64 slice Philips Brilliance iCT scanner (Philips Healthcare, Best, The Netherlands). A single observer quantified the percentage diameter stenosis (% DS) manually using cross sectional images at the most severe site of narrowing and in the proximal non-diseased reference arterial segment. From these two images, % DS was calculated as (1 – L/R) × 100, where L is minimum lesion diameter and R is diameter at the proximal reference site.
5
Coronary Artery Calcium Scoring
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All patients were scanned using a 256-detector-row Brilliance iCT scanner (Philips Healthcare, Cleveland, OH) in July 2010. The entire heart was covered in a single breath-hold (20–30 sec). Slices of 3.0-mm thickness were acquired with 150 mA of tube current at 120 kV. Quantification was performed by a single trained reader who was blinded to the clinical data, using software for calcium scoring (Heartbeat-CS, EBW, Philips Medical Systems, Best, The Netherlands). This software can detect calcified lesions with a density of at least 130 Hounsfield units (HU) over a minimal area of 0.5 mm2. Patients were assigned calcification scores based on the number, area, and peak HU of the calcific lesions, as described by Agatston et al[28] (link). (1: 110–199 HU; 2: 200–299 HU; 3: 300–399 HU; 4: >400 HU). Data obtained during the diastolic phase of the heart cycle were used for image reconstruction. The total score was calculated by summing the calcification scores of the left main, left anterior descending, left circumflex, and right coronary arteries.
6
Post-Operative Lumbar Spine Screw Evaluation
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Postoperative CT was performed 1 month after surgery in all patients to evaluate the implant position and the coronal and sagittal reformatting of the lumbar spine. A 256 channel-Philips Brilliance i-CT scanner was used to obtain 3.0 mm-thick sections with a field of view adequate for visualization of the spine. The screw position was assessed by independent observers (one neurosurgeon and one radiologist). The evaluation of screw placement was performed according to the criteria devised by Learch et al.10) (link) The screw position was classified as "cortical encroachment" (or questionable violation) if the pedicle cortex could not be visualized or as "frank misplacement" when the screw was outside the pedicle boundary. Frank misplacement was further classified according to the distance that the edge of the screw thread extended outside the pedicle cortex; the screws were classified as minimally misplaced (≤2.0 mm), moderately misplaced (2.1-4 mm or <1 screw thread diameter), or severely misplaced (>4 mm or >1 screw diameter). Bilateral pedicle screws were usually placed in the S1 vertebra and were therefore not included in our misplacement analysis.
7
CCTA Quantification of Atherosclerotic Plaque
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CCTA was performed using a 256-slice Brilliance iCT scanner (Philips Healthcare, Hamburg, Germany) that features a gantry rotation time of 270 ms, resulting in a temporal resolution of 36–135 ms, depending on the heart rate of the patient, and an isotropic sub-millimetre spatial resolution of 0.67×0.67×0.67 mm3. The CCTA protocol and quantitative assessment of atherosclerotic plaque components is described in detail elsewhere [21 (link),22 (link)]. Patients without any plaque or stenosis were considered patients „without CAD“.
8
Chest CT Imaging Protocol Comparison
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In the training set, non-contrast enhanced CT images of the chest were obtained from three different manufacturers: Philips (https://www.philips.com.cn/healthcare ), General Electric (GE, https://www.gehealthcare.cn ) and Siemens (https://www.siemens-healthineers.cn ) Medical Systems, respectively. In the validation set, CT images were acquired using a 256-layer Brilliance iCT scanner from Philips. CT image scanning parameters: tube voltage, 110–120 kV; tube current, 100–150 mAS; rotational speed, 0.5 s; reconstructed slice thickness, 1–5 mm; matrix, 512*512; kernel function, standard.
9
Phantom CT Scanning Protocol Optimization
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The phantoms were scanned using a 256-slice Brilliance iCT scanner (Philips Healthcare, Cleveland, Ohio, USA). The following parameters were held constant for each scan: collimation 128 × 0.625 mm, field of view (FOV) 350 mm, matrix 512 × 512, slice thickness of 1 mm and increment of 0.5 mm. The phantoms were scanned at 80, 120 and 140 kV. Scans were performed at 10, 50, 100, 150, 200, 250, 300 and 350 mA for each X-ray tube voltage. Scans were also performed at 400 and 450 mA for 80 and 120 kV. These currents were not available on the scanner for 140 kV. The raw data was obtained from the scanner and reconstructed off-site using either filtered back-projection (Standard), iDose (Level 4) or IMR algorithms, referred to as FBP, ITER and IMR respectively (the algorithms are directly comparable since they were all sourced from Philips Healthcare, Cleveland, Ohio, USA). This created a total of 174 sets of images. A schematic depiction of the data acquisition and analysis process is given in Supplementary Figure 1 .
10
Standardized CT Imaging Protocol for Tumor Assessment
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All CT studies were performed with contrast agents, and they followed a standardized protocol on one of the three CT systems: Brilliance iCT scanner (Philips Healthcare), uCT 760 (United Imaging), and SOMATOM Perspective (Siemens Healthineers). The main scanning parameters were as follows: tube voltage = 120 kV, automatic tube current modulation (30–70 mAs), pitch = 1.0–1.5. mm, matrix = 512 × 512, slice thickness = 5 mm, field of view 350 × 350 mm. All images were reconstructed to 0.625–1.25-mm thickness. Other findings of imaging studies, such as brain MRI or 18F-fluorodeoxyglucose PET/CT, were also reviewed to identify new lesions and assess non-target lesions.
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