Mr750 3.0 tesla mr scanner

MRI scans were performed using an MR750 3.0 Tesla MR scanner (GE Healthcare, Milwaukee, WI, USA). Resting-state functional imaging data were acquired using a gradient-echo echo-planar imaging sequence with the following parameters: repetition time (TR) = 2000 ms, echo time (TE) = 30 ms, field of view = 240 × 240 mm², matrix = 64 × 64, flip angle (Cupaioli et al., 2021) = 90°, voxel size = 3.75 × 3.75 × 4.00 mm³, 39 slices, and 255 volumes. Before the scanning, all the participants were asked to relax, think of nothing in particular, keep their eyes closed, and avoid sleeping. After scanning, the participants were asked whether they fell asleep to try to ensure that they kept awake during the entire scanning.

Structural images were acquired on a General Electric MR750 3.0-Tesla MR scanner with a 12-channel head coil. We acquired 1 T1-weighted 3-dimensional Magnetization Prepared-Rapid Gradient Echo scan per participant (scanning parameters: repetition time (TR)/echo time (TE) 7,312/3.02 ms, flip angle 11°, 256 × 256 matrix, 1.2-mm thick, 196 sagittal slices, field of view = 270). Cortical thickness, surface area, volume, and local gyrification index as well as subcortical volumes were quantified using FreeSurfer 6.0.0 (http://surfer.nmr.mgh.harvard.edu). The procedure has been described in detail elsewhere (64 (link)–68 (link, link, link, link)). Smoothing was performed with a 10-mm kernel at full width/half max (FWHM) for cortical thickness, surface area, and volume. As local gyrification index already is a smooth measure, we only applied a 5-mm FWHM kernel for smoothing.