Microcoils

Manufactured by Cook Medical

Sourced in United States

Microcoils are small medical devices designed for interventional radiological procedures. They are made of a metal alloy and are used to occlude or embolize blood vessels. Microcoils can be delivered through a catheter to the target location within the body.

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Lab products found in correlation

Celsite, by B. Braun (1 mentions) 0.035 inch guidewire, by Terumo (1 mentions)

3 protocols using microcoils

Cyanoacrylate Embolization of Gastric Varices

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Subsequently, a Cobra catheter was inserted into the major feeding vessels of the gastric varices from the portal vein system, such as the coronary gastric vein, posterior gastric vein, or short gastric vein, and a microcatheter was introduced when needed. Then, the cyanoacrylate was directly injected into the gastric varices and their feeding vessels through the catheter under X-ray guidance.
In this study, 2-OCA mixed with 50% lipiodol was used to obliterate the gastric varices. It was slowly injected into the gastric varices under fluoroscopic guidance. Once the gastric varices were completely obliterated, the catheter was slowly withdrawn. The balloon occlusive catheter was then deflated and removed.
Splenoportography was again performed to assess the obliteration of the varices. If any feeding veins (such as the short or posterior gastric veins) were still present, the procedure was repeated until the gastric varices and feeding veins were completely filled with cyanoacrylate.
Finally, the puncture tract within the liver parenchyma was simultaneously embolized with microcoils (Cook Medical, Bloomington, IN, USA). Low molecular weight heparin (100 IU/kg body weight) was subcutaneously administered 24 h after the procedure and daily for 7 d to prevent portal venous thrombosis.

Wang G., Meng D., Huang G., Pei Q., Zhao L., Shi Y., Zhang M., Feng H., Zhang J, & Zhang C. (2019). Balloon-Assisted Percutaneous Transhepatic Antegrade Embolization with 2-Octyl Cyanoacrylate for the Treatment of Isolated Gastric Varices with Large Gastrorenal Shunts. BioMed Research International, 2019, 2674758.

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Hepatic Artery Infusion Chemotherapy Protocol

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The procedure was implemented under local anesthesia, accessing either through the right femoral or the left subclavian artery. Utilizing the Seldinger technique, a catheter was introduced into the arterial lumen over a 0.035-inch guidewire (Terumo, Tokyo, Japan). Angiography was performed on celiac, superior mesenteric, and extrahepatic arteries that fed the tumor, if present, to assess the anatomy of the hepatic blood supply and tumor arteries. Before HAIC port implantation, collateral branches from extrahepatic arteries were occluded to enhance treatment efficacy. Microcoils (Tornado, Cook, USA) were used to embolize the right gastric artery to prevent chemotherapeutic agents from refluxing into the stomach. A 5 Fr port and catheter (Celsite, B. Braun Medical, Pennsylvania, USA) were placed in the common hepatic artery before the distal end of the catheter was fixed to the gastroduodenal artery using Microcoils. After each cycle of HAIC therapy, 3,000–5,000 U of heparin were injected into the port to prevent catheter occlusion (17 (link)).

Hien P.N., Chun H.J., Oh J.S., Kim S.H, & Choi B.G. (2024). Hepatic arterial infusion chemotherapy for hepatocellular carcinoma refractory to transarterial chemoembolization: exploring the influence of prior transarterial chemoembolization and additional transarterial chemoembolization on survival outcomes. Journal of Gastrointestinal Oncology, 15(2), 721-729.

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Angiographic Embolization for Tumor

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An initial angiographic survey was performed by an interventional radiologist to identify the bronchial artery branches that supplied the tumour. Selective arterial embolization of the corresponding arteries was then performed using foam particles (poly-vinyl alcohol 200-900 μm) with or without microcoils (Cook Medical, Bloomington, Ind., USA).

Salamonsen M., Tazi-Mezalek R., López-Lisbona R., Cubero N., Baixeras N., Dominguez J., Dorca J, & Rosell A. (2016). Combined Bronchial Artery Embolization and Endobronchial Resection for Bronchial Carcinoid: A Safety and Feasibility Pilot Study. Respiration; international review of thoracic diseases, 91(1).

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