The spherical equivalent refractive error, corneal curvatures, and axial dimensions of each eye of each monkey were measured before lens-wearing (at 23±3 days of age), monthly during the lens-wearing treatment period, and at the age of puberty (at 1185+3 days of age). To make these measurements, the monkeys were anesthetized with a combination of ketamine hydrochloride + acepromazine maleate (10 mg/kg + 0.2 mg/kg, respectively, intramuscular). Retinoscopy was performed by two experienced optometrists using a streak retinoscope and hand-held trial lens, after topical application of three drops of 0.5% tropicamide for cycloplegia. Mean spherical equivalent spectacle-plane refractive correction was recorded for a given eye’s refractive status. Corneal curvature was assessed using a handheld videotopographer (Vista; EyeSys, Houston, TX). The axial dimensions were measured by A-scan ultrasonography (AXIS-II; Quantel Medical Inc., Clermont-Ferrand, France); the 11-MHz transducer was placed in direct contact with the cornea, following topical anesthesia with one drop of 0.4% oxybuprocaine hydrochloride. The details of these determinations have been reported previously[12 (link)]. All the examiners in our experiment were blinded to the animal groups and each other’s findings.
Axis 2
Manufactured by Lumibird Medical
Sourced in France
The AXIS-II is a high-precision optical coherence tomography (OCT) system designed for laboratory and research applications. The device utilizes advanced optical imaging technology to capture detailed, cross-sectional images of samples with micrometer-level resolution.
Automatically generated - may contain errors
Lab products found in correlation
3 protocols using axis 2
1
Refractive Changes in Primate Myopia
2
Longitudinal A-Scan Ultrasound in Guinea Pigs
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A-scan ultrasound with a 25-MHz probe (AXIS-II; Quantel Medical Inc., Clermont- Ferrand, France) as performed on guinea pigs at baseline and on days 7, 14, and 21. The right eye was anesthetized with proparacaine hydrochloride drops and the guinea pig was restrained manually. The examiner placed the ultrasound probe on the corneal surface at the center of the pupil and recorded the values. For each measurement, at least five traces were captured per eye and analysed offline. All measurements were done by the same skilled examiner.
3
Glaucoma Diagnosis and Optic Nerve Assessment
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For this study, 77 eyes of 77 normal subjects and 97 eyes of 97 open angle glaucoma subjects who had visited the cataract and glaucoma clinic of Boramae Medical Center, Seoul, Korea, from June 1, 2016 to July 31, 2016, were consecutively selected, and their medical records were retrospectively reviewed. At the initial work-up, each of the subjects underwent a complete ophthalmologic examination, including a review of medical history, measurement of best-corrected visual acuity, refraction by autorefractor keratometer (KR-8100; Topcon, Tokyo, Japan), slit-lamp biomicroscopy, gonioscopy, intraocular pressure measurement with a Goldmann applanation tonometer, dilated stereoscopic examination of the optic disc, and red-free fundus photography (VX-10; KOWA, Tokyo, Japan). In addition, Humphrey VF examination using the Swedish interactive threshold algorithm standard 30-2 test (HVF C30-2; Humphrey 720i Visual Field Analyzer, Carl Zeiss Meditec, Dublin, CA, USA), optical coherence tomography (Cirrus HD-OCT, Carl Zeiss Meditec), and axial length measurement by immersion ultrasound (Axis II; Quantel Medical, Clermont-Ferrand, France) were performed at the next follow-up. The study was approved by the institutional review board of Boramae Medical Center, Seoul, Korea (16-2017-34), and was conducted with adherence to the Declaration of Helsinki.
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