N decylmaltoside

Manufactured by Anatrace

N-decylmaltoside is a non-ionic detergent commonly used for the solubilization and stabilization of membrane proteins in biochemical and biophysical studies. It has a hydrophilic maltose headgroup and a hydrophobic decyl alkyl chain, which allows it to effectively solubilize and maintain the native structure of integral membrane proteins.

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Lab products found in correlation

1 palmitoyl 2 oleoyl sn glycero 3 phosphoethanolamine, by Avanti Polar Lipids (2 mentions) 1 palmitoyl 2 oleoyl sn glycero 3 phospho 1 rac glycerol popg, by Avanti Polar Lipids (2 mentions) N dodecyl maltoside, by Anatrace (1 mentions) Escherichia coli polar lipid extract, by Avanti Polar Lipids (1 mentions)

Spelling variants of this product

N-decylmaltoside (DM), (2 citations)

2 protocols using n decylmaltoside

Lipid Bilayer Reconstitution Protocol

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Phospholipids (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine [POPE], 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol [POPG], and Escherichia coli polar lipid extract) used in reconstitution and lipid bilayer recordings were from Avanti Polar Lipids, Inc. EDANS (5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid) C2 maleimide was from AnaSpec. Detergents used in purification (n-decylmaltoside and n-dodecylmaltoside) were from Anatrace.

Turman D.L, & Stockbridge R.B. (2017). Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies. The Journal of General Physiology, 149(4), 511-522.

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Lipid Membrane Preparation Protocol

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All reagents were purchased from Sigma-Aldrich or Fischer Scientific at the highest quality available. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho(1′-rac-glycerol) (POPG), and E. coli polar lipids (EPL) were purchased from Avanti Polar Lipids. EDANS C2 maleimide was purchased from Molecular Probes, and n-decyl maltoside (DM) was purchased from Anatrace.

Turman D.L., Cheloff A.Z., Corrado A.D., Nathanson J.T, & Miller C. (2018). Molecular Interactions between a Fluoride Ion Channel and Synthetic Protein Blockers. Biochemistry, 57(7), 1212-1218.

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