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Neoplastin

Manufactured by Diagnostica Stago
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Sourced in France

Neoplastin is a laboratory reagent used in the measurement of prothrombin time (PT) as part of coagulation testing. It is a thromboplastin, a complex of phospholipids and proteins that activates the extrinsic pathway of the coagulation cascade. Neoplastin is used to evaluate the function of the coagulation system and assess the risk of bleeding or thrombosis.

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Lab products found in correlation

Sta liquid fib, by Diagnostica Stago (1 mentions) Citrate tubes, by BD (1 mentions)

2 protocols using neoplastin

1

Hemostasis Evaluation: Coagulation Markers

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Prothrombin time (PT) (Neoplastin, Diagnostica Stago, Asnières sur Seine, France) and activated partial thromboplastin time (aPTT) (PTT-A, Diagnostic Stago, Asnières sur Seine, France) were measured with STAR Max. Fibrinogen levels were measured in plasma by Clauss clotting method (STA-Liquid Fib, Diagnostica Stago, Asnières, France). All hemostasis tests were performed in citrated plasma samples.
Feugray G., Kasonga F., Grall M., Dumesnil C., Benhamou Y., Brunel V., Le Cam Duchez V., Lahary A, & Billoir P. (2022). Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease. Frontiers in Cardiovascular Medicine, 9, 883812.
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2

INR Testing in Coagulation Analysis

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Laboratory testing was performed at the National Health Laboratory Service Hematology Laboratory at CMJAH. The INR testing was performed by venepuncture collected in citrate tubes (Becton-Dickinson, Oxford, United Kingdom) and measured within 2 hours of collection on the STA-R evolution coagulation analyzers (Diagnostica Stago, Asnières, France) with Neoplastin (Diagnostica Stago) reagents with an international sensitivity index of ∼0.94. All INR measurements ≥5 were checked manually.
Schapkaitz E., Louw S., Friedman J., Sithole J., Masebe M, & Jacobson B.F. (2018). Conservative Management of Overanticoagulation in Patients With Low–Moderate Risk for Bleeding Complications. Clinical and Applied Thrombosis/Hemostasis, 24(8), 1255-1260.
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