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Clofarabine

Manufactured by Bio-Techne
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Sourced in Germany

Clofarabine is a nucleoside analog used as a laboratory research tool. It is a synthetic compound that inhibits DNA and RNA synthesis, and has been utilized in various cell-based assays and research applications.

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Lab products found in correlation

Gemcitabine, by Selleck Chemicals (1 mentions) Ly2603618, by Bio-Techne (1 mentions) Aphidicolin, by Selleck Chemicals (1 mentions) Ku55933, by Selleck Chemicals (1 mentions) Nu7441, by Bio-Techne (1 mentions) Vismodegib, by MedChemExpress (1 mentions) Decitabine, by Bio-Techne (1 mentions) Cytarabine, by Bio-Techne (1 mentions) Ganetespib, by MedChemExpress (1 mentions) Fludarabine, by Bio-Techne (1 mentions) Venetoclax, by MedChemExpress (1 mentions) Daunorubicin, by Selleck Chemicals (1 mentions) Cladribine, by Bio-Techne (1 mentions) Gedatolisib, by Selleck Chemicals (1 mentions) Volasertib, by Selleck Chemicals (1 mentions) Olaparib, by MedChemExpress (1 mentions)

2 protocols using clofarabine

1

Chemical Compound Procurement for Research

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Chemical compounds were purchased from Sigma (gemcitabine, KU55933, and aphidicolin), Selleck Chemicals (LY2603618 and clofarabine), and Tocris (AZ20 and NU7441).
Goss K.L., Koppenhafer S.L., Harmoney K.M., Terry W.W, & Gordon D.J. (2017). Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine. Oncotarget, 8(50), 87016-87032.
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2

Evaluation of nucleoside analogs

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CNDAC was purchased from biorbyt (via Biozol, Eching, Germany), 5-azacytidine, cytarabine, cladribine, clofarabine, decitabine, and fludarabine from Tocris Biosciences (via Bio-Techne GmbH, Wiesbaden, Germany), 6-thioguanine, ganetespib, molibresib, olaparib, sapacitabine, venetoclax, and vismodegib from MedChemExpress (via Hycultec, Beutelsbach, Germany), daunorubicin, gedatolisib, and volasertib from Selleckchem (Berlin, Germany), gemcitabine from Hexal (Holzkirchen, Germany), GTP and dATP from Thermo Scientific (Dreieich, Germany), and CNDAC-TP from Jena Bioscience GmbH (Jena, Germany).
Rothenburger T., Thomas D., Schreiber Y., Wratil P.R., Pflantz T., Knecht K., Digianantonio K., Temple J., Schneider C., Baldauf H.M., McLaughlin K.M., Rothweiler F., Bilen B., Farmand S., Bojkova D., Costa R., Ferreirós N., Geisslinger G., Oellerich T., Xiong Y., Keppler O.T., Wass M.N., Michaelis M, & Cinatl J J.r. (2021). Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells. Journal of Experimental & Clinical Cancer Research : CR, 40, 317.
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