Ftir 8201 pc

The required chemicals in this
work were purchased from Merck Sigma-Aldrich
and Loba chemicals. All melting points were uncorrected and determined
on a Fisher–John apparatus. Elemental analyses were performed
at the Micro Analytical Center of Chemistry Department, Assiut University,
Egypt. The FT-IR spectra were recorded using potassium bromide disks
on a FT-IR8201PC Shimadzu. H and C nuclear magnetic resonance (NMR)
spectra were recorded on Bruker BioSpin GmbH spectrometers and Varian
Mercury VX-300NMR (¹H 400 MHz, ¹³C NMR 100 MHz)
in CDCl₃ and DMSO-d₆ using
tetramethylsilane (Me₄Si) as the internal standard. Chemical
shifts were expressed as ppm. Mass spectra were measured on a Joel-JMS
600 spectrometer at Chemistry Department—Assiut University,
Egypt. All reactions were monitored by the thin-layer chromatography
technique on silica gel-coated aluminum sheets (Silica gel60 F₂₅₄, Merck). The amino isothiochromene carbonitrile compound 1 was synthesized according to the literature procedure.^{38 (link)}