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B6 mrl fas lpr j b6 lpr mice

Manufactured by Jackson ImmunoResearch

B6.MRL-Fas lpr /J (B6.lpr) mice are a strain of genetically modified mice that have a spontaneous mutation in the Fas gene. This mutation leads to the development of a lymphoproliferative disorder, characterized by the accumulation of abnormal lymphocytes in various organs. These mice are commonly used in research related to autoimmune diseases and apoptosis.

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3 protocols using b6 mrl fas lpr j b6 lpr mice

1

Murine Models for Immunological Research

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C57BL/6 J (B6) mice, B6(C)-H2-Ab1bm12/KhEgJ (bm12), B6.CgTg (TcraTcrb) 425Cbn/J (OT-II), B6.SJL-PtprcaPepcb/BoyJ (B6.SJL) and B6.MRL-Faslpr/J (B6.lpr) mice were obtained from the Jackson Laboratory. All mice were bred and maintained at the University of Florida in specific pathogen-free conditions. Both males and females were used between 2 and 6 months of age. Gender and age were matched for each experiment. D-mannose (Sigma) was dissolved at 1.1 M in drinking water and administered ad lib.
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2

Mannose Regulates Immune Response

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Mice C57BL/6J (B6) mice, B6(C)-H2-Ab1 bm12 /KhEgJ (bm12), B6.CgTg (TcraTcrb) 425Cbn/J (OT-II), B6.SJL-Ptprc a Pepc b /BoyJ (B6.SJL) and B6.MRL-Fas lpr /J (B6.lpr) mice were obtained from the Jackson Laboratory. All mice were bred and maintained at the University of Florida in speci c pathogen-free conditions. Both males and females were used between 2 and 6 months of age. Gender and age were matched for each experiment. D-mannose (Sigma) was dissolved at 1.1 M in drinking water and administered ad lib.
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3

Mannose Regulates Immune Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Mice C57BL/6J (B6) mice, B6(C)-H2-Ab1 bm12 /KhEgJ (bm12), B6.CgTg (TcraTcrb) 425Cbn/J (OT-II), B6.SJL-Ptprc a Pepc b /BoyJ (B6.SJL) and B6.MRL-Fas lpr /J (B6.lpr) mice were obtained from the Jackson Laboratory. All mice were bred and maintained at the University of Florida in speci c pathogen-free conditions. Both males and females were used between 2 and 6 months of age. Gender and age were matched for each experiment. D-mannose (Sigma) was dissolved at 1.1 M in drinking water and administered ad lib.
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