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Recombinant human nrg1

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Recombinant human NRG1 is a protein produced in a laboratory setting. It is a member of the neuregulin protein family, which play a role in the development and function of various cells and tissues.

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Lab products found in correlation

Pi 103, by Selleck Chemicals (1 mentions) Gsk2578215a, by Bio-Techne (1 mentions) Colchicine, by Merck Group (1 mentions) Poly 1 c, by InvivoGen (1 mentions) Mli 2, by Abcam (1 mentions) Lrrk2 in 1, by Bio-Techne (1 mentions) Recombinant human ifn γ, by R&D Systems (1 mentions) Mg132, by Merck Group (1 mentions) Ionomycin, by Merck Group (1 mentions) Phorbol myristate acetate (pma), by Merck Group (1 mentions) Lipopolysaccharides (lps), by InvivoGen (1 mentions)

2 protocols using recombinant human nrg1

1

High-Throughput Drug Screening Assays

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Reversible EGFR/ErbB2 RTK inhibitor Lapatinib (Cat. S1028), irreversible pan-ErbB RTK inhibitor Poziotinib (Cat. S7358), and PI3K/Akt/mTOR inhibitor PI-103 (Cat. S1038) were purchased from Selleckchem (Houston, TX). Recombinant human NRG1 was acquired from BioLegend (San Diego, CA, Cat. 551904). High-throughput drug screening assays were used with compounds sourced as indicated in Suppl. Table 1.
Ippolitov D., Lin Y.H., Spence J., Glogowska A., Thanasupawat T., Beiko J., Del Bigio M.R., Xu X., Wang A., Calvo R., Kapoor A., Marugan J.J., Henderson M.J., Klonisch T, & Hombach-Klonisch S. (2024). Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis. bioRxiv.
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2

Stimulating Cell Responses with Diverse Agents

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Where indicated, cells were treated with recombinant human IFN-γ (R&D Systems), LPS (LPS from E. coli O111:B4), poly(I:C) (both Invivogen), ionomycin, MG132, colchicine, PMA (all from Sigma-Aldrich), LRRK2-IN-1 and GSK2578215A (both Tocris), Mli-2 (Abcam), MCV1 (HPVIVIT, Calbiochem), recombinant human NRG1 (BioLegend), and PTX (STEMCELL Technologies).
Panagiotakopoulou V., Ivanyuk D., De Cicco S., Haq W., Arsić A., Yu C., Messelodi D., Oldrati M., Schöndorf D.C., Perez M.J., Cassatella R.P., Jakobi M., Schneiderhan-Marra N., Gasser T., Nikić-Spiegel I, & Deleidi M. (2020). Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells. Nature Communications, 11, 5163.
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