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18 protocols using 202 height measure

1

Anthropometric Measurements and BMI Classification

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BMI values were determined by dividing weight in kilograms by the square of height in metres. Weight was measured using the Tanita BC-418 MA body composition analyser and standing height using a Seca 202 height measure as part of the initial assessment visit [18 ]. BMI (kg/m2) was classified according to the World Health Organization (WHO) categories:  <18.5 (underweight), ≥18.5 to <25 (normal weight), ≥25 to 30 (overweight), ≥30 to <35 (obesity class I), ≥35 to <40 (obesity class II), and ≥40 (obesity class III) [19 ].
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2

Biomarker Measurement Protocol

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Diastolic and systolic blood pressure (DBP; SBP) were assessed using digital
blood pressure monitors (HEM-7015IT; Omron Healthcare Inc.). We used the second
reading because there is evidence the first reading can overestimate blood
pressure.8 (link)Weight was measured, to the nearest 0.1 kg, using the Tanita BC-418 MA body
composition analyser. Height was measured using a Seca 202 height measure. Body
mass index (BMI) was derived as weight (kg)/[height (m)×height (m)] by UK
Biobank centrally. Participants removed their shoes and heavy outer clothing
before weight and height were measured.
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3

Cardiometabolic Outcomes and Obesity Measures

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BMI was calculated using measured height and weight with the formula weight (kg)/height (m) squared (Keys et al., 1972 (link)). Standing was measured using a Seca 202 height measure. A single weight measurement was taken after participants removed their shoes, socks/tights, heavy outer clothing and emptied their pockets using a Tanita BC-418 MA body composition analyzer. Correlations of BMI with absolute fat mass measured by densitometry range from 0.82 to 0.91(Spiegelman et al., 1992 (link)). BMI was categorized as underweight (<18.5), normal range (18.5–24.9), overweight (≥25.0–29.9) and obese (≥30.0) (World Health Organization, 2015 ).
Single survey items were used to assess the diagnosis of cardiometabolic diseases including heart attack, angina, stroke, hypertension and diabetes. Each diagnosis was coded as yes, no or don’t know/prefer not to answer. Daytime dozing/narcolepsy was coded as yes (often/all the time) or no (never/rarely/sometimes) and sleeplessness/insomnia was coded as yes (usually) or no (never/rarely/ sometimes).
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4

Diabetes, Anthropometry, and Cardiovascular Risk

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The presence of diabetes was based on a self-reported medical diagnosis. Age at first diagnosis of diabetes, and the use of medications for cholesterol, blood pressure or diabetes regulation were self-reported at study baseline. Type I diabetes was defined as the presence of the combination of a self-reported medical diagnosis of diabetes, an age at first diagnosis before 30 years, and the use of an insulin product. All other participants with a self-reported medical diagnosis of diabetes were considered to have type II diabetes. Smoking status was self-reported. Socioeconomic status was measured using the Townsend Deprivation Score, an area of residence-based index of material deprivation. Baseline physical measurements were obtained by trained staff using standardised procedures and regularly calibrated equipment. Blood pressure was measured using the Omron HEM-7015IT digital blood pressure monitor. Standing height was measured using a Seca 202 height measure. Waist and hip circumference were measured using a Wessex non-stretchable sprung tape measure. Weight and body fat percentage were measured using the Tanita BC-418 MA body composition analyser. BMI was calculated by dividing weight (kg) by the square of the standing height (m2). Waist-to-hip ratio was derived by dividing the waist circumference by the hip circumference.
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5

Comprehensive Biometric Assessment Protocol

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Blood pressure and heart rate were measured using the Omron HEM-70151T digital blood pressure monitor. Two measurements of each were taken and the mean was used in subsequent analysis. Weight was measured with the Tanita BV-418 MA body composition analyser. Height was measured using a Seca 202 height measure. Body mass index (BMI) was calculated as weight/height2. Waist circumference at the level of the umbilicus was measured using a Wessex non-stretchable sprung tape measure. Baseline visual acuity was measured using a computerised semiautomated LogMAR system at 3 m, with best available correction.
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6

Comprehensive Health Assessment Protocol

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Participants answered a detailed touch-screen questionnaire which included information regarding their age, gender, ethnicity, education, household income, history of disease and surgery, use of vitamin supplement (yes/no), as well as lifestyle factors, including sleep duration (hours/day), alcohol drinking (never/previous/current) and smoking status (never/former/current). Physical activity (PA) was assessed using the short form International Physical Activity Questionnaire [21 (link)], and the metabolic equivalent (MET)- minutes/week of PA was calculated based on their answers to time spent on walking, moderate PA and vigorous PA. Weight was measured with the BV-418 MA body composition analyser (Tanita), and height was measured in a barefoot standing position using a Seca 202 height measure. Body mass index was calculated based on measured weight (kg) divided by measured height (m) squared. Depression was recorded during the interview with a research nurse. Blood cholesterols, including triglycerides, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), were measured by direct enzymatic methods ((Konelab, Thermo Fisher Scientific, Waltham, Massachusetts), and Glycosylated haemoglobin, Type A1C (HbA1c)) was measured using high-performance liquid chromatography on a Bio-Rad Variant II Turbo.
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7

Birth Weight to Adulthood Obesity Patterns

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Individuals recalled their BW either in kilograms directly, or in imperial pounds and ounces and converted to kilograms. We categorized BW into three groups according to the World Health Organization definition (<2.5 kg as LBW, 2.5–4.0 kg as NBW, and ≥4.0 kg as HBW) [21 ]. Adult body weight was measured by a variety of means using the Tanita BC-418 MA body composition analyzer, and standing height measured using a Seca 202 height measure. Adult BMI was derived from body weight in kilograms divided by standing height in meters, and adult obesity was defined by the cutoff value of BMI at 30.0 kg/m2 (BMI >30.0 kg/m2 as OB and BMI ≤30.0 kg/m2 as NOB). We further ranked our participants into percentiles according to birthweight and current body weight at recruitment, separately, and calculated individual percentile change in body weight from birth to adulthood, as well as percentile change of BW-to-adult BMI (Supplementary Fig. 1). Six birth-to-adulthood body weight tracking patterns were defined by different combinations of three BW categories and obesity status in adulthood, including (1) LBW-to-OB, (2) LBW-to-NOB, (3) NBW-to-OB, (4) NBW-to-NOB, (5) HBW-to-OB, and (6) HBW-to-NOB.
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8

Comprehensive Health Measurements in Baseline Visit

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Health related measurements were also recorded during the baseline visit. Weight was measured using Tanita BC-418MA body composition analyzer and height with Seca 202 height measure, and they were used to calculate the body mass index (BMI; kg/m2). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured, using Omron HEM-705 IT digital blood pressure monitor, twice with 1-min interval between the two measurements. The average SBP and DBP were calculated and used in the analyses. Diabetes was defined using the ICD-10 primary/main diagnosis codes from hospital inpatient records: E10–E14.
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9

Standardized Anthropometric Measurements

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Trained staff used standardized procedures and regularly calibrated equipment to obtain the body size measurements. Waist circumference at the level of the umbilicus was measured using a Wessex nonstretchable sprung tape measure. Hip circumference was measured using the same tape measure. Standing height was measured with a Seca 202 height measure after participants had removed their shoes. Body weight was measured using the Tanita BC‐418 MA body composition analyzer after shoes and heavy outer clothing were removed. BMI was calculated by dividing weight (kilograms) over height (meters) squared; waist‐to‐hip ratio was calculated by dividing the waist circumference by the hip circumference; and waist‐to‐height ratio was calculated by dividing the waist circumference by standing height.
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10

Obesity Determination via BMI Measurement

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BMI was estimated with baseline height, which was measured to the nearest 0.1 centimeter (cm) using a Seca 202 height measure, and baseline weight, which was measured to the nearest 0.1 kilogram (kg) using a Tanita BC418MA body composition analyzer. Obesity was defined as BMI ≥ 30 kg/m2, in accordance with the WHO criteria [26 ]. In present study, participants who met the criteria of obesity but not sarcopenia at baseline were categorized into obesity group.
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