Polysorbate 80

Manufactured by Sinopharm

Sourced in China

Polysorbate 80 is a non-ionic surfactant commonly used as an emulsifier in various laboratory applications. It is a viscous, yellow liquid that is soluble in water and oil. Polysorbate 80 is primarily utilized to improve the solubility and stability of other compounds in aqueous or lipid-based solutions.

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Lab products found in correlation

Penicillin, by Thermo Fisher Scientific (2 mentions) Streptomycin, by Thermo Fisher Scientific (2 mentions) Dspe peg2000, by Lipoid (1 mentions) Curcumin, by Merck Group (1 mentions) Chloroform, by Sinopharm (1 mentions) Formaldehyde, by Nanjing Chemical Reagent (1 mentions) Phenol, by Nanjing Chemical Reagent (1 mentions) Petroleum ether, by Sinopharm (1 mentions) Paraformaldehyde (pfa), by Sinopharm (1 mentions) Anti neun antibody mab377, by Merck Group (1 mentions) H2o2 assay kit, by Beyotime (1 mentions) Lipid peroxidation mda assay kit, by Beyotime (1 mentions) Total glutathione assay kit, by Beyotime (1 mentions)

3 protocols using polysorbate 80

Curcumin-loaded Cerasome-based Microbubbles

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All chemicals and lipids were commercially available and used as obtained. Cerasome-forming lipid (CFL), N-[N-(3-triethoxysilyl)propylsuccinamoyl]-di-hexadecylamine, was synthesized according to the reported method 47 , 50 . Curcumin was purchased from Sigma Aldrich (Steinheim, Germany). The organic solvents, chloroform, and polysorbate 80 were purchased from Sinopharm Chemical Reagent, China. Distearoyl phosphatidylcholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (DSPE-PEG2000; Lipoid, Ludwigshafen, Germany) were used for microbubble synthesis according to the reported method 31 (link), 64 (link). Dulbecco's modified Eagle's medium (DMEM), fetal bovine serum, penicillin, and streptomycin were all purchased from Thermo Fisher Scientific, USA. All other reagents were of analytical grade. The C57BL/6 mice, weighing about 20 g (6 weeks old), were obtained from Guangdong Medical Experimental Animal Center (Guangzhou, China). All the animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) and carried out ethically and humanely.

Zhang N., Yan F., Liang X., Wu M., Shen Y., Chen M., Xu Y., Zou G., Jiang P., Tang C., Zheng H, & Dai Z. (2018). Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy. Theranostics, 8(8), 2264-2277.

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Synthesis of Flame-Retardant Phenolic Resin

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Phenol (P > 99%), formaldehyde (37 wt %), calcium oxide (CaO), and sodium hydroxide (NaOH) were obtained from Nanjing Chemical Reagent, Ltd. (Nanjing, China). 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) was obtained from Shenzhen jinlong chemical technology Co., Ltd. (Shenzhen, China). Itaconic acid (ITA), Deuterium dimethylsulfoxide (d₆-DMSO) and ethyl cellulose (EC) were purchased from Aladdin (Shanghai, China). Polysorbate-80, petroleum ether, and Paraformaldehyde (≥95%) were obtained from Sinopharm group Chemical Reagent Co. Ltd. (Shanghai, China). Mixed acid curing agent were obtained from Institute of Chemical Industry of Forestry Products, Chinese Academy of Forestry (Nanjing, China).

Ma Y., Gong X., Liao C., Geng X., Wang C, & Chu F. (2018). Preparation and Characterization of DOPO-ITA Modified Ethyl Cellulose and Its Application in Phenolic Foams. Polymers, 10(10), 1049.

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Chitosan Nanoparticle Cerebral Protection

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Chitosan (85% deacetylation, molecular weight 10⁵ Da) was purchased from Zhejiang Jinke Biochemistry (Zhejiang, China). Rhodamine B isothiocyante (RBITC) was obtained from Sigma-Aldrich (USA). Sodium tripolyphosphate (TPP) was purchased from Shijiazhuang Shinearly Chemicals (China). Polysorbate 80 was obtained from Sinopharm Chemical Reagent (China). The following kits were purchased from Beyotime (Haimen, China): H₂O₂ assay kit (S0038), total glutathione assay kit (S0052), and lipid peroxidation MDA assay kit (S0131). Anti-NeuN antibody (MAB377) was purchased from Millipore (MA, USA). Rabbit anti-GFAP was obtained from Wuhan Boster Company (Wuhan, China).

Yuan Z.Y., Hu Y.L, & Gao J.Q. (2015). Brain Localization and Neurotoxicity Evaluation of Polysorbate 80-Modified Chitosan Nanoparticles in Rats. PLoS ONE, 10(8), e0134722.

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