Chloroauric acid hydrate

MEO₂MA, OEGMA, bis[2-(2′-broMoisobutyryloxy)-ethyl]disulfide (BiBOEDS), silver trifluoroacetate (CF₃COOAg) and poly(vinylpyrrolidone) (PVP, M_w=55kD) were obtained from Sigma-Aldrich Corp (St Louis, MO, USA). Tris(2-dimethyl-aminoethyl)amine (Me₆TREN) and anhydrous sodium hydrosulfide (NaHS) were purchased from Alfa Aesar (Shanghai, China). Ethylene glycol (EG, purity>99.0%), cuprous chloride (CuCl), chloroauric acid hydrate (HAuCl₄·4H₂O, Au content>47.8%) and 4'6-diamidino-2-phenylindole (DAPI) were purchased from Sinopharm Chemical Reagent Co., Ltd (Beijing, China). DMEM, RPMI 1640 and fetal bovine serum (FBS) were obtained from Gibco BRL/Life Technologies (Grand Island, NY, USA). pHLIP (ACEQNPIYWARYADWLFTTPLLLLDLALLVDADEGT) was synthesized by Bankpeptide Inc. (Heifei, China). All other reagents were of analytical grade and used without any further purification.

Chloroauric acid hydrate (HAuCl₄·4H₂O, analytical grade), l-ascorbic acid (AA, analytical grade), sodium bromide (NaBr, analytical grade), cetyltrimethyl ammonium bromide (CTAB, analytical grade) and octadecyltrimethyl ammonium bromide (OTAB, analytical grade) were all purchased from Sinopharm Chemical Reagent Co. Ltd (Shanghai, China). Palladium(ii) chloride (PdCl₂, analytical grade) was provided by Shanghai Fine Chemical Materials Institute. Phosphate buffer solution (PBS) was prepared with tablets obtained from Sinopharm Chemical Reagent Co. Ltd (Shanghai, China). 30% w/w hydrogen peroxide (H₂O₂, analytical grade) was received from Guangzhou Jinhuada Chemical Reagent Co. Ltd. H₂PdCl₄ solution was prepared by dissolving PdCl₂ in HCl solution followed by dilution with ultrapure water. All reagents were used as received without further purification. All aqueous solutions were prepared with ultrapure water with a resistivity of 18.2 MΩ cm⁻¹.