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Fe 3 chloride hexahydrate

Manufactured by Merck Group
Sourced in United States

Fe(III) chloride hexahydrate is a chemical compound with the formula FeCl3•6H2O. It is a crystalline solid that is used as a reagent in various laboratory applications. The compound provides a source of iron(III) ions and chloride ions, which can be utilized in different experimental and analytical procedures.

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5 protocols using fe 3 chloride hexahydrate

1

Synthesis of Magnetic RAFT Nanoparticles

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Reversible addition-fragmentation chain-transfer (RAFT) agents 2-[(butylsulfanyl)carbonothioyl]sulfanyl propanoic acid (C 4 -RAFT) and methoxy-polyethylene glycol modi ed 2-[(butylsulfanyl)carbonothioyl] sulfanyl propanoic acid were kindly provided by Dr Algi Serelis (DuluxGroup). Fe(II) chloride tetrahydrate (99%), Fe(III) chloride hexahydrate (98%), Fe(III) nitrate nonahydrate (99%), acrylamide (>98%), rhodamine B isothiocyanate (>70%), DOX (>98%) and nitric acid (HNO 3 , 65%, Suprapur®, Millipore) were purchased from Sigma-Aldrich (St. Louis, USA). Ammonium hydroxide (28% NH 3 in water) and sodium hydroxide (NaOH) (>98%) were obtained from Ajax Finechem (Australia). 1,4-Dioxane (Fluka-Sigma-Aldrich, St Louis, USA), monoacryloxyethyl phosphate (MAEP, >98%, PolySciences, Warrington, USA) and 4,4azobis(4-cyanovaleric acid) (Wako, USA) were used as received.
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2

RAFT-Mediated Polymer Synthesis and Drug Delivery

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Reversible addition-fragmentation chain-transfer (RAFT) agents 2-[(butylsulfanyl)carbonothioyl]sulfanyl propanoic acid (C 4 -RAFT) and methoxy-polyethylene glycol modified 2-[(butylsulfanyl)carbonothioyl]sulfanyl propanoic acid were kindly provided by Dr Algi Serelis (DuluxGroup). Fe(II) chloride tetrahydrate (99%), Fe(III) chloride hexahydrate (98%), Fe(III) nitrate nonahydrate (99%), acrylamide (> 98%), rhodamine B isothiocyanate (> 70%), DOX (> 98%) and nitric acid (HNO 3 , 65%, Suprapur ® , Millipore) were purchased from Sigma-Aldrich (St. Louis, USA). Ammonium hydroxide (28% NH 3 in water) and sodium hydroxide (NaOH) (> 98%) were obtained from Ajax Finechem (Australia). 1,4-Dioxane (Fluka-Sigma-Aldrich, St Louis, USA), monoacryloxyethyl phosphate (MAEP, > 98%, PolySciences, Warrington, USA) and 4,4-azobis(4-cyanovaleric acid) (Wako, USA) were used as received.
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3

Synthesis of Iron-based Nanoparticles

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Fe(II) chloride tetrahydrate (99%) and Fe(III) chloride hexahydrate (98%) were purchased from Sigma-Aldrich Co. (St Louis, MO, USA) and used as supplied. Fe(III) nitrate nonahydrate (99%) was from EMD Millipore, Billerica, MA, USA and used as supplied. Ammonium hydroxide (28% NH3 in water, w/w) was purchased from Ajax Finechem (Thermo Fisher Scientific, Waltham, MA, USA). RAFT agents 2-{[(butylsulfanyl)carbonothioyl]sulfanyl}propanoic acid (RAFT-COOH) and methoxy polyethylene glycol modified 2-{[(butylsulfanyl)carbonothioyl]sulfanyl} propanoic acid (RAFT-MPEG) were provided by Dr Algi Serelis (DuluxGroup, Melbourne, Australia). Fluka – 1,4-dioxane was distilled under reduced pressure. MAEP (Sigma-Aldrich Co.) was passed through an inhibitor removal column (Sigma-Aldrich Co.). AAm (Sigma-Aldrich Co.), 4,4′-azobis(4-cyanovaleric acid) (V-501; Sigma-Aldrich Co.), and sodium hydroxide (NaOH; Sigma-Aldrich Co.) were used as received. Milli-Q (MQ) water was used throughout the work. 2H2O was from the Australian Nuclear Science and Technology Organisation (ANSTO; Lucas Heights, NSW, Australia).
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4

Synthesis of Magnetic Nanoparticles

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All solvents were of analytical grade and used with no modifications. Fe(III) chloride hexahydrate, Fe(II) chloride tetrahydrate, Mn(II) chloride tetrahydrate, Zn(II) chloride, trisodium citrate dihydrate, ammonium hydroxide and epoxy resin kit were purchased from Sigma-Aldrich. Dextran (70 kDa) was purchased from Carl Roth. Ultrapure water produced with a
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5

Synthesis and Characterization of Metal-Organic Frameworks

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Fe(III) chloride hexahydrate (FeCl3·6H2O; 98%), 2‐aminoterephthalic acid (BDC‐NH2; 99%), N,N‐dimethylformamide (DMF; anhydrous, 99.8%), d‐penicillamine (d‐pen; 98%–101%), 4‐chloro‐7‐nitrobenzofurazan (NBD‐CL; 98%), copper(II) sulfate (CuSO4; >99%), formic acid (>98%) and 2′‐7′‐dichlorofluorescein diacetate (DCFH‐DA) were purchased from Sigma‐Aldrich (St. Louis, MO, USA). Methanol (>96%), ethanol (>96%), ammonium acetate (98%), sodium borate (Na2B4O7), and hydrogen peroxide (H2O2; 30%–35%) were obtained from Daejung Chemicals (Siheung, Korea). 3,3′,5,5′‐Tetramethylbenzidine (TMB; >98%) and acetonitrile (ACN, 99.9%) were purchased from TCI (Chuo‐ku, Japan) and J.T. Bakers (Pittsburgh, PA, USA), respectively. Irinotecan (CPT‐11; >99%) was obtained from LC Laboratories (Woburn, MA, USA). Phosphate‐buffered saline (PBS, pH 7.4) and Dulbecco's Modified Eagle's Medium (DMEM) were obtained from the Seoul National University Biomedical Research Institute (Seoul, Korea) and Welgene (Gyeongsan, Korea), respectively. Fetal bovine serum (FBS) and penicillin–streptomycin (10,000 U/ml) were purchased from Thermo Fisher Scientific (Waltham, MA, USA).
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