In this study, the treatment plan quality was evaluated by a set of pre-defined dosimetric parameters for different RT techniques. This study was given IRB approval by the First People’s Hospital of Changzhou. Written informed consent was obtained from the patients before treatment. The methods used were in compliance with the guidelines in the Declaration of Helsinki. Fifteen early stage breast cancer patients with left-side lesion treated in our institution were retrospectively selected. Four of the studied patients had inner quadrant tumor, which were included in additional separate analyses. Patients were treated in supine position on a wing board with arms positioned above the head. Planning CT scans with 3 mm slice thickness were acquired using a Siemens Somatom Sensation Open 40-slice CT scanner (Siemens Medical Solutions, Forchheim, Germany). The image data sets were imported into a Monaco Treatment Planning System (Monaco version3.3, Elekta AB, Stockholm, Sweden) for planning. An X-ray voxel Monte Carlo algorithm16 (link) was used for dose calculation with grid size: 3 × 3 × 3 mm3.
Somatom sensation open 40
Manufactured by Siemens
Sourced in Germany
The Somatom Sensation Open 40 is a computed tomography (CT) scanner manufactured by Siemens. It is designed to capture high-quality images of the human body for diagnostic purposes. The device utilizes advanced imaging technology to produce detailed scans of internal structures and organs.
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Lab products found in correlation
2 protocols using somatom sensation open 40
1
Evaluating Treatment Plan Quality in Early-Stage Breast Cancer
2
Chemoradiotherapy for Gastric Cancer
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All patients underwent CT-based radiation treatment planning. Bowel preparation had been done before CT simulation (200 ml water with urografin after 4 h empty stomach). Patients were immobilized in vacuum pad (klarity) during the CT scan. And the CT (SIEMENS Somatom Sensation Open 40) scan range was from 4 cm up to diaphragm muscle to the lower edge of fourth lumbar vertebrae with a slice thickness of 3 mm. Radiotherapy was administered by intensity-modulated radiation therapy (IMRT) or three dimensional conformal radiation therapy (3DCRT) technique, using 6-MV photons. During the treatment, almost the whole pancreas was irradiated. The protocol for treatment was referred to INT-0116 [9] . The treatment regions included the gastric bed, anastomosis and regional lymph nodes (gastric, celiac, gastroduodenal, porta hepatis, splenic, peripancreatic, pancreaticoduodenal and para-aortic A2B1 group). The prescription dose ranged from 45Gy to 50.5Gy which was delivered in 25 fractions (5 fractions per week for 5 weeks). The concurrent chemotherapy regimen was based on 5-fluorouracil (5-FU) (intravenous fluorouracil 400 mg/m 2 and leucovorin 200 mg/m 2 in the first 4 and the last 3 days of the radiotherapy).
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