Synthetic 1,2-dilauroyl-sn-glycero-3-phosphcocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DLPG), 1,2-dimyrsitoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DMPG), 1,2-dipalmitoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DPPG), 1,2-distearoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DSPG), 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG), 1,2-distearoyl-3-trimethylammonium-propane (DSTAP), 1,2-dipalmitoyl-3-trimethylammonium-propane (DPTAP), and glucopyranosyl lipid adjuvant (GLA, also known as PHAD®) were purchased from Avanti Polar Lipids Inc. (Alabaster, AL). Polysorbate 80 was purchased from J.T. Baker (San Francisco, CA). Poloxamer 188 was purchased from Spectrum Chemical (Gardena, CA). Saline solution (0.9% w/v) was purchased from Teknova (Hollister, CA). CpG ODN was obtained from Avecia (Milfrod, MA). Alhydrogel® ‘85’ and AdjuPhos® were purchased from E.M. Sergeant Pulp & Chemical Co. (Clifton, NJ). 3M-052 (S-36862) was synthesized by 3M Drug Delivery Systems. The chemical structure has been previously disclosed [16] (link).
Glucopyranosyl lipid adjuvant
Manufactured by Avanti Polar Lipids
Glucopyranosyl lipid adjuvant is a lipid-based compound developed by Avanti Polar Lipids. It is designed to serve as an adjuvant, which is a substance that enhances the immune response to an antigen. The core function of the glucopyranosyl lipid adjuvant is to stimulate the immune system, but its specific applications and intended uses are not provided here.
Automatically generated - may contain errors
Lab products found in correlation
1 2 dipalmitoyl 3 trimethylammonium propane dptap, by Avanti Polar Lipids (2 mentions)
Saline solution, by Teknova (1 mentions)
Polysorbate 80, by Avantor (1 mentions)
Poloxamer 188, by Spectrum Chemical (1 mentions)
Phosphate buffered saline (pbs), by Thermo Fisher Scientific (1 mentions)
Imiquimod, by InvivoGen (1 mentions)
1 2 dipalmitoyl sn glycero 3 phosphocholine, by Avanti Polar Lipids (1 mentions)
Lactic acid, by Merck Group (1 mentions)
1 2 dioleoyl sn glycero 3 phosphocholine dopc, by Avanti Polar Lipids (1 mentions)
2 protocols using glucopyranosyl lipid adjuvant
1
Synthetic Lipids and Adjuvants for Vaccine Formulations
2
Lipid-based Adjuvant Formulations
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Milled imiquimod (IMQ) was purchased from Chemagis (Bnei Brak, Israel); imiquimod was also obtained from Invivogen (San Diego, CA). Glucopyranosyl lipid adjuvant (GLA), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol (DPPG), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), and 1,2,dipalmitoyl-3-trimethylammonium-propane (DPTAP) were purchased from Avanti Polar Lipids Inc. (Alabaster, AL). DOPC was also purchased from Lipoid (Newark, NJ). Cholesterol, and ammonium phosphate mono- and dibasic were purchased from J.T. Baker (San Francisco, CA). Lactic acid was purchased from Sigma-Aldrich (St. Louis, MO). Phosphate buffered saline (PBS) at pH 7.2 was purchased from Life Technologies (Grand Island, NY).
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