Lactate plus

Manufactured by Nova Biomedical

Sourced in United States

The Lactate Plus is a portable blood lactate analyzer designed for rapid and accurate measurement of lactate levels. It provides reliable and consistent results, enabling healthcare professionals to monitor and manage patient conditions effectively.

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Close spelling variants of this product

Lactate Plus Meter (48 citations) Lactate Plus lactate meter (14 citations) Lactate Plus analyzer (9 citations) Lactate Plus Meter Test Strips (3 citations) Lactate Plus test strips (2 citations) Lactate Plus Blood Lactate Measuring Meter (2 citations) Lactate plus™ handheld (2 citations)

68 protocols using lactate plus

Measuring Whole-Blood Lactate Levels

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Whole-blood lactate [La^–] concentration was measured immediately before, immediately post, and 5 min post exercise for all four trials utilizing a portable lactate analyzer (Lactate Plus, Nova Biomedical Corporation, Waltham, MA, United States) and lactate test strips (Lactate Plus, Nova Biomedical Corporation, Waltham, MA, United States). Blood samples of about 5 μl were collected through finger pricks performed in the index or middle fingers. Before the blood was collected, the finger was swiped with alcohol, and the first drop was discarded. The lactate analyzer was calibrated every day before data collection using low and high lactate standards (Lactate Plus, Nova Biomedical Corporation, Waltham, MA, United States), following the manufacture’s recommendations. [La^–] levels were posteriorly corrected for plasma volume shifts using the following equation:
here [La^–]_c stands for corrected lactate concentration, [La^–]_un stands for uncorrected lactate concentration, and %PVΔ stands for percent changes in plasma volume.

Freitas E.D., Miller R.M., Heishman A.D., Ferreira-Júnior J.B., Araújo J.P, & Bemben M.G. (2020). Acute Physiological Responses to Resistance Exercise With Continuous Versus Intermittent Blood Flow Restriction: A Randomized Controlled Trial. Frontiers in Physiology, 11, 132.

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Whole-blood Lactate Measurement in Exercise

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Whole-blood lactate was measured using a portable lactate analyzer (Lactate Plus, Nova Biomedical Corporation, Waltham, MA, United States) at baseline, immediately post-, 5 min post-, and 15 min post-exercise. Blood samples of approximately 5 μl were collected through finger pricks performed in the index or middle fingers. Before collecting the blood, the finger was wiped with alcohol and the first droplet was discarded. The lactate analyzer was calibrated every day before data collection using low and high lactate standards (Lactate Plus, Nova Biomedical Corporation, Waltham, MA, United States), following the manufacture’s recommendations. The day-to-day reliability for baseline WBL levels was ICC = 0.494. WBL values were corrected for changes in plasma volume and used for statistical analysis.

Freitas E.D., Galletti B.R., Koziol K.J., Miller R.M., Heishman A.D., Black C.D., Bemben D, & Bemben M.G. (2020). The Acute Physiological Responses to Traditional vs. Practical Blood Flow Restriction Resistance Exercise in Untrained Men and Women. Frontiers in Physiology, 11, 577224.

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Incremental 200m Swimming Test

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The first stage of the test started at the speed associated with 200 m TT minus 0.35 m.s - 1 , and was increased in the subsequent stages by 0.05 m.s -1 until exhaustion occurred (9) . Inbetween 200 m steps, a 30 s rest interval was allowed for blood sampling ([La -] from an earlobe). Pace was controlled with a Finis Tempo Trainer (Finis Inc., California, USA) that was preprogramed to the pace required to swim each 50 m in order to ensure that the swimmers swam their expected 200 m time evenly. Time to complete each 200 m stage (Finis Inc., 3 x 100 m, California, USA), [La -] (Lactate Plus, Nova Biomedical, Waltham, USA), rating of perceived exertion (RPE, 1-10 Borg scale) and HR (A300, Polar, USA) were collected at the end of each 200 m stage.

Piatrikova E., Sousa A.C., Willsmer N.J., Gonzalez J.T, & Williams S. (2020). Demarcating Exercise Intensity Domains in Freestyle Swimming: Is There an Alternative to Incremental Step Test and Beats Below HRmax Method?. Journal of strength and conditioning research, 34(9).

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NIRS Assessment of HIIE Muscle Oxygenation

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A near infra-red spectroscopy (NIRS) device (Moxy, Moxy Monitor System, MN) was used to measure muscle tissue oxygenation every second during each HIIE session. The highest muscle tissue oxygenation value from each active rest period (MTO active rest %) was averaged for each HIIE session. Additionally, the lowest muscle tissue oxygenation (MTO during HIIE%) value per high intensity bout was recorded and averaged from each HIIE session. The difference of the average MTO active rest % and MTO during HIIE% was used to calculate the muscle tissue oxygenation difference (MTO difference %). All MTO measurements were taken on the dominant leg at a marked location on the vastus lateralis that would allow movement without interference from the NIRS device. A pulse oximeter (Caretaker, Caretaker Medical, Charlottesville, VA) was used to measure SpO 2 during HIIE. Blood lactate measurements (Lactate Plus, NOVA Biomedical, MA) were taken in duplicate at the ear lobe immediately before, and 5-minutes post HIIE.

Wells A., Fennel Z., Ducharme J., Masoud A., Houck J., Bellovary B., Deyhle M., Hsiao Y.Y., Amorim F, & Mermier C. (2022). Facemask Use During High Intensity Interval Exercise in Temperate and Hot Environments. Journal of occupational and environmental medicine, 64(5).

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Cerebrospinal Fluid Lactate Analysis in Canine Epilepsy

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Cerebrospinal fluid samples were collected from dogs that were referred to the NC State Veterinary Hospital for epileptic seizures as part of a routine diagnostic evaluation. The samples were obtained from the cerebellomedullary cistern or lumbar subarachnoid space in a routine manner. Most samples were analyzed immediately using a commercially available lactate monitor (Lactate Plus, Nova Biomedical, Waltham, Massachusetts) although some were evaluated after being frozen at −80°C, which has little effect on lactate concentration.⁴

Mariani C.L., Nye C.J., Ruterbories L., Tokarz D.A., Green L., Lau J., Zidan N., Early P.J., Muñana K.R., Olby N.J., Lee C, & Guevar J. (2020). Cerebrospinal fluid lactate concentrations in dogs with seizure disorders. Journal of Veterinary Internal Medicine, 34(6), 2562-2570.

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Muscle Damage and Inflammation Markers

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Blood lactate concentrations were collected using a portable lactate meter (Lactate Plus, Nova Biomedical Corporation, Waltham, MA). Samples were obtained from a finger at baseline and after finishing the leg curl, seated row, and pull down. Samples were obtained in duplicate. A second blood sample was collected from an antecubital forearm vein at baseline, immediately following the recovery period and at 24 hours post-exercise. Creatine Kinase (CK) concentrations were measured to estimate muscle damage using an enzyme linked immunosorbent assay (ELISA). Inflammatory cytokine levels were measured using a Milliplex MAP kit of Human Cytokines/ Chemokine (Millipore Corp; Billerica, MA) for the simultaneous quantification of several cytokines including IL-1α, IL-6 and TNFα. These cytokines were chosen for their potential roles in modulating skeletal muscle mass [14 (link)] and post- exercise inflammation. [15 (link)] Samples were run in duplicate; if one sample was markedly different than the other, a third sample was analyzed.

Vincent H., Percival S., Creasy R., Alexis D., Seay A., Laura Ann Z., MacMillan M, & Vincent K. (2014). Acute Effects of Enhanced Eccentric and Concentric Resistance Exercise on Metabolism and Inflammation. Journal of novel physiotherapies, 4(2), 200.

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Lactate-Pyruvate Tolerance and Gluconeogenesis

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Lactate/Pyruvate tolerance tests were performed as previously described (29) . Briefly, mice were fasted for 16 hours overnight and given an IP injection of a 1.5mg/g of a 10:1 sodium lactate: sodium pyruvate solution. 40% of the sodium lactate and sodium pyruvate were [U- 13 C] sodium lactate and [U- 13 C] sodium pyruvate. Blood glucose was measured 0, 10, 20, and 30 minutes post injection using a blood glucometer (Contour Next) and lactate was measured using a lactate meter (Nova Biomedical Lactate Plus). Fractional gluconeogenesis (GNG) was determined as previously described (67), using the following formula:
where Mx represents the fractional enrichment of the m+x species for the indicated metabolite.

Lesner N.P., Wang X., Chen Z., Frank A.R., Menezes C.J., House S., Shelton S.D., McFadden D.G., Wansapura J., DeBerardinis R.J., & Mishra P. (2021). Differential requirements for mitochondrial electron transport chain components in the adult murine liver.

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Measuring Blood Lactate Levels

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Blood lactate concentrations were recorded immediately before and after exercise (i.e., before cool-down) during all trials. Capillary blood samples (approximately 25 μL) were acquired from the fingertips using a portable analyser (Lactate Plus, Nova Biomedical, Waltham, MA, USA).

Poon E.T., Sun F.H., Chung A.P, & Wong S.H. (2018). Post-Exercise Appetite and Ad Libitum Energy Intake in Response to High-Intensity Interval Training versus Moderate- or Vigorous-Intensity Continuous Training among Physically Inactive Middle-Aged Adults. Nutrients, 10(10), 1408.

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Blood Lactate Measurement During Exercise

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Blood lactate was assessed at baseline, immediately following the last repetition of the 6^th set for the BS and BP exercises and immediately following the anaerobic sprint test. Samples were collected using Mumford Uni-stick 3 (Owen Mumford, UK) normal single use safety lancets and assessed using a handheld lactate analyzer (Lactate Plus, Nova Biomedical, MA, USA).

Jagim A.R., Jones M.T., Wright G.A., St. Antoine C., Kovacs A, & Oliver J.M. (2016). The acute effects of multi-ingredient pre-workout ingestion on strength performance, lower body power, and anaerobic capacity. Journal of the International Society of Sports Nutrition, 13, 11.

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Metabolic and Lactate Responses to HIIT

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In addition, measures of participants’ energy expenditures (EE), cumulative EEs, and metabolic equivalent (MET) were used in both estimation procedures, with measurement via indirect calorimetry using PNOE. Blood lactate concentrations were recorded immediately before and after the AHIIT or LHIIT in all trials. Capillary blood samples (approximately 25 µL) were acquired from the fingertips using a portable analyzer (Lactate Plus, Nova Biomedical, Waltham, MA, USA).

Kwok M.M., Poon E.T., Ng S.S., Lai M.C, & So B.C. (2022). Effects of Aquatic versus Land High-Intensity Interval Training on Acute Cardiometabolic and Perceptive Responses in Healthy Young Women. International Journal of Environmental Research and Public Health, 19(24), 16761.

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