Prisma 3.0t

Manufactured by Siemens

Sourced in Germany

Prisma 3.0T is a magnetic resonance imaging (MRI) system designed and manufactured by Siemens. It operates at a magnetic field strength of 3.0 Tesla, which provides high-quality imaging for various clinical applications. The core function of Prisma 3.0T is to generate detailed and high-resolution images of the human body, enabling healthcare professionals to diagnose and monitor various medical conditions.

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Lab products found in correlation

Discovery mr750 3.0t, by GE Healthcare (2 mentions) Magnetom aera 1.5t, by Siemens (1 mentions) Dotarem, by Guerbet (1 mentions) Gadodiamide, by GE Healthcare (1 mentions) Optima mr360 1.5t, by GE Healthcare (1 mentions) Ingenia 3.0t, by Philips (1 mentions) Syngo via, by Siemens (1 mentions) Trio 3.0 tesla whole body mri scanner, by Siemens (1 mentions)

14 protocols using prisma 3.0t

Comprehensive Cardiovascular MRI Protocol

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CMR was performed using either a Magnetom Aera 1.5T or Prisma 3.0T system (Siemens Healthineers, Erlangen, Germany). A standard CMR protocol was used including cine images, stress and rest perfusion and late gadolinium enhancement.21 (link) All subjects abstained from caffeine for at least 12 hours. Adenosine was infused for 4 min at 140 µg/kg/min (increased to 175 µg/kg/min if there was no heart rate response and symptoms). At peak vasodilator stress a gadolinium-based contrast agent (Dotarem, Guerbet, Paris, France) was injected at a dose of 0.05 mmol/kg at a rate of 4 mL/s. Three short axis slices (base, mid and apex) were acquired during the first pass of contrast (60 measurements). The acquisition was repeated at rest, with the short axis cine stack acquired between stress and rest.
Perfusion mapping was performed automatically and inline as previously described.15 (link) In brief, this was a single-bolus, dual-sequence technique with a balanced steady-state free precession (bSSFP) pulse sequence readout. LGE images were acquired in long axis and short axis using a free-breathing bright blood single-shot bSSFP sequence with phase-sensitive inversion recovery reconstruction and motion correction. Sequence details are provided in the supplementary appendix.

Camaioni C., Knott K.D., Augusto J.B., Seraphim A., Rosmini S., Ricci F., Boubertakh R., Xue H., Hughes R., Captur G., Lopes L.R., Brown L.A., Manisty C., Petersen S.E., Plein S., Kellman P., Mohiddin S.A, & Moon J.C. (2019). Inline perfusion mapping provides insights into the disease mechanism in hypertrophic cardiomyopathy. Heart, 106(11), 824-829.

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Uterine MRI Imaging Protocol

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All MRI studies were performed with 3.0 T MRI systems, including Siemens Magnetom Verio 3.0 T (Erlangen, Germany), Philips Ingenia 3.0 T (Veenpluis, The Netherlands), and Siemens Prisma 3.0 T (Erlangen, Germany). A region of interest (ROI) was segmented around the whole uterus on sagittal T2W turbo spin-echo images and axial DW images with b = 800 s/mm 2 . The related MR acquisition parameters are listed in Table 1.

Han Y., Xu H., Ming Y., Liu Q., Huang C., Xu J., Zhang J, & Li Y. (2020). Predicting myometrial invasion in endometrial cancer based on whole-uterine magnetic resonance radiomics. Journal of cancer research and therapeutics, 16(7).

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Multimodal Neuroimaging Protocol for Cerebrovascular Assessment

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All patient imaging tests were performed using a Siemens Prisma 3.0 T (Siemens, Germany) magnetic resonance scanner with a 32-channel head coil.
The scanning protocols comprised conventional brain and cerebrovascular imaging. Conventional brain imaging encompassed T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), and fluid-attenuated inversion-recovery (FLAIR). Cerebrovascular imaging involved 3-dimensional time-of-flight MRA (3D TOF MRA) and HR vascular wall imaging technology, specifically the three-dimensional sampling perfection with application-optimized contrasts using different flip angle evolution (3D-SPACE) sequence for HR-VWI. The contrast medium was meglumine gadolinium pyrospermate (Gd-DTPA) and was given via a bolus in an elbow vein at an amount of 0.2 mL/kg body weight. The imaging parameters of these sequences were as follows: (1) T1WI: Repetition time (TR)/ echo time (TE): 2000/7.4 ms, field of view (FOV) 220 × 220; slice thickness 5 mm, and slice number 20; (2) T2WI: TR/TE: 4000/117 ms, FOV 220 × 220; slice thickness 5 mm, and slice number 20; (3) FLAIR: TR/TE: 9000/81 ms, FOV 220 × 220; slice thickness 5 mm, and slice number 20; (4) 3D-TOF MRA: TR/TE: 21/3.4 ms, FOV 200 × 200; slice thickness 0.7 mm, and slice number 40; and (5) 3D-SPACE: Sagittal imaging orientation, TR/TE: 900/14 ms, FOV 240 × 240; slice thickness 0.6 mm, and slice number 224.

Mo Y.Q., Luo H.Y., Zhang H.W., Liu Y.F., Deng K., Liu X.L., Huang B, & Lin F. (2024). Investigating the relationship between intracranial atherosclerotic plaque remodelling and diabetes using high-resolution vessel wall imaging. World Journal of Diabetes, 15(1), 72-80.

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Neuroimaging Protocol for Siemens Prisma 3T

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All participants underwent T1 and DTI imaging on a Siemens Prisma 3.0 T magnetic resonance scanner (Siemens Medical System, Erlangen, Germany) at Fujian Province Rehabilitation Hospital. The parameters of T1 imaging were as follows: repetition time (TR) = 2,300 ms, echo time (TE) = 2.27 ms, flip angle = 8°, slice thickness = 1.0 mm, field of view (FOV) = 250 × 250 mm, matrix = 256 × 256, voxel size = 0.98 × 0.98 × 1 mm³, and number of slices = 160. For DTI, the parameters were as follows: TR = 8,000 ms, TE = 64 ms, FOV = 224 × 224 mm, slice thickness = 2.0 mm, gap = 0 mm, slice number = 75, and slice order = interleaved.

Wan M., Ye Y., Lin H., Xu Y., Liang S., Xia R., He J., Qiu P., Huang C., Tao J., Chen L, & Zheng G. (2021). Deviations in Hippocampal Subregion in Older Adults With Cognitive Frailty. Frontiers in Aging Neuroscience, 12, 615852.

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Comprehensive MRI Liver Imaging Protocol

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MRI scans of the abdomen at baseline and follow-up of all patients were performed on three scanners: GE Discovery MR 750 3.0T, GE Pioneer 3.0T, and Siemens Prisma 3.0T. Routine liver MRI protocol included non-fat suppressed coronal single-shot fast/turbo spin-echo T2WI (SS-FSE/HASTE), axial fat suppressed fast/turbo spin echo (FSE/TSE) T2WI, T1WI in- and out-of- phase, DWI and dynamic CE-T1WI images. For dynamic CE-T1WI, unenhanced, early and late arterial phases (using fluoro trigger or carebolus technique), portal venous phase (60s), late venous phase (180s) were obtained using a 3D T1WI breath-hold fat-suppressed spoiled gradient-recall echo sequence (LAVA or VIBE) before and after intravenous administration of gadodiamide (0.5 mmol/ml, GE Healthcare) at a dose of 0.2 ml/kg body weight and an injection rate of 2ml/s. Respiratory-triggered or diaphragm-navigated DWI with an axial single-shot spin echo, echo-planar imaging (EPI) sequence with DW gradients (b value 0/50 and 800 s/mm²) was applied in three orthogonal directions (slice thickness/space: 6.0/1.0 mm, FOV: 34−38 cm, matrix size: 128×128, NEX: 4).

Xu Y., Yang Y., Li L., Ye F, & Zhao X. (2022). The α-RECIST (RECIST 1.1 Combined With Alpha Fetoprotein): A Novel Tool for Identifying Tumor Response of Conversion-Radiotherapy for Unresectable Hepatocellular Carcinoma Before Hepatectomy. Frontiers in Oncology, 12, 905260.

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Tai Chi-Induced Gray Matter Changes

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Each participant completed the baseline and post-intervention MRI scans 1 week before commencement and 1 week after completion of the Tai Chi training or waitlist control, respectively. The scanning procedures were explained, and informed consent was obtained from the participants. MRI data acquisition covered T1-weighted high-resolution anatomical images using a Siemens Prisma 3.0 T. T1-weighted structural images were acquired with a three-dimensional magnetization-prepared rapid acquisition gradient-echo sequence, sagittal scanning (TR/TE/FOV = 2000 ms/1.73 ms/240 mm × 240 mm, flip angle = 15 degrees, layers = 160, layer thickness = 1 mm, and imaging matrix = 256 × 256). Data processing included preprocessing of the MRI data using the Statistical Parametric Mapping 12 (SPM 12) and the Computational Anatomy Toolbox 12 (CAT12) (http://dbm.neuro.uni-jena.de/cat12/) programs. High-dimensional Diffeomorphic Anatomical-Registration-Through-Exponentiated Lie-Algebra image registration was performed for nonlinear registration with the gray matter template of the standard Montreal Neurological Institute 152 space [62 (link)]. The normalized and segmented gray matter image was modulated and smoothed using isotropic Gaussian smoothing with a 10-mm full width at half maximum.

Wu J., Song J., He Y., Li Z., Deng H., Huang Z., Xie X., Wong N.M., Tao J., Lee T.M, & Chan C.C. (2023). Effect of Tai Chi on Young Adults with Subthreshold Depression via a Stress–Reward Complex: A Randomized Controlled Trial. Sports Medicine - Open, 9, 90.

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Standardized MRI Protocols for Liver Imaging

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MRI studies were performed following standardized protocols on GE Optima MR360 1.5T, GE Discovery MR750 3.0T, GE SIGNA Architect 3.0T, and Siemens Prisma 3.0T scanners. MRI contrast agents included gadobenate dimeglumine, gadodiamide, gadobutrol, and gadoxetate disodium and were administered according to the manufacturer-recommended weight-based doses.
All patients underwent MRI examination procedures. Respiratory training was performed before examination, and end-expiratory scans were obtained. All patients underwent routine plain MRI (including axial T1WI, T2WI, and DWI) and contrast-enhanced scans (dynamic contrast-enhanced), and arterial, portal, and delayed phase images were acquired by injecting recommended dosage body mass of contrast medium with an equivalent volume of saline through the cubital vein at a 3-mm/s flow rate using a high-pressure injector and bolus injection of contrast material. Hepatobiliary phase images were acquired at 20 min.

Zeng Q., Xie S., He X., Guo Y., Wu Y., He N., Zhang L., Yu X., Zheng R, & Li K. (2024). FI-CEUS: a solution to improve the diagnostic accuracy in MRI LI-RADS-indeterminate (LR-3/4) FLLs at risk for HCC. Frontiers in Oncology, 13, 1225116.

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Multimodal MRI Acquisition for Brain Imaging

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3D T1W structural images were acquired at our center with two different scanners: the Ingenia 3.0T (Philips, Amsterdam, The Netherlands) (P) and Prisma 3.0T (Siemens, Munich, Germany) (S). The acquisition program was as follows: resolution = 1 × 1 × 1 mm, field of view = 256 × 256 mm, slice thickness = 1 mm, flip angle = 8°, repetition time = 6.49/1.56 s, and echo time = 3.042/1.56 ms (for P/S). In addition, conventional magnetic resonance (MR) sequences including T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR) and T1W images with intravenous injection of a gadolinium contrast agent were routinely acquired.

Huang Z., Li G., Li Z., Sun S., Zhang Y., Hou Z, & Xie J. (2021). Contralesional Structural Plasticity in Different Molecular Pathologic Subtypes of Insular Glioma. Frontiers in Neurology, 12, 636573.

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Resting-state fMRI and structural MRI protocol

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Each participant completed a resting-state scan and a high-resolution anatomic scan. We collected MRI data using a Siemens Prisma 3.0 T whole-body scanner at Beijing Anding Hospital of Capital Medical University. Participants were instructed to lie still inside the scanner, close their eyes, stay awake and try not to think about anything in particular. For each participant, we acquired 200 volumes of fMRI images using an echo-planar imaging sequence with the following parameters: repetition time 2000 ms, echo time 30 ms, field of view 200 × 200 mm, matrix 64 × 64, flip angle 90°, number of slices 33, slice thickness 3.5 mm, slice spacing 0.7 mm. We acquired a sagittal T₁-weighed structural scan to co-register it with the fMRI data, using the following parameters: repetition time 2530 ms, echo time 1.85 ms, matrix 256 × 256, field of view 256 × 256 mm, slice thickness 1 mm, flip angle 9°.

Wang Y., Chen X., Liu R., Zhang Z., Zhou J., Feng Y., Zeidman P., Wang G, & Zhou Y. (2022). Disrupted effective connectivity of the default, salience and dorsal attention networks in major depressive disorder: a study using spectral dynamic causal modelling of resting-state fMRI. Journal of Psychiatry & Neuroscience : JPN, 47(6), E421-E434.

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High-Resolution 3D MRI and Functional Imaging

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High-resolution 3D MRI is performed on a 3T MRI scanner (Prisma 3.0T, Siemens, Erlangen, Germany). MRI T₁ images are acquired with a 3D magnetization-prepared rapid gradient echo sequence with the following parameters: repetition time = 3000 ms, echo time = 2.56 ms, flip angle = 7°, acquisition matrix = 320 × 320, in-plane resolution = 0.8 × 0.8 mm², slice thickness = 0.8 mm and sagittal slices = 208.
High spatiotemporal resolution fMRI scans are obtained by using a multislice single-shot gradient echo planar imaging sequence: 488 volumes, repetition time = 800 ms, echo time = 37 ms, flip angle = 52°, field of view = 208 × 208 mm², sagittal slices = 72 without slice gaps and matrix size = 2 × 2 × 2 mm³. The subjects are instructed to close their eyes but remain awake during the scanning.

Liu M., Huang Q., Huang L., Ren S., Cui L., Zhang H., Guan Y., Guo Q., Xie F, & Shen D. (2024). Dysfunctions of multiscale dynamic brain functional networks in subjective cognitive decline. Brain Communications, 6(1), fcae010.

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