Tosyl chloride

Manufactured by Merck Group

Sourced in United States

Tosyl chloride is a chemical compound commonly used as a reagent in organic synthesis. It serves as a sulfonating and acylating agent, facilitating the introduction of various functional groups into organic molecules. Tosyl chloride is widely utilized in pharmaceutical, agrochemical, and fine chemical industries.

Automatically generated - may contain errors

Lab products found in correlation

5 protocols using tosyl chloride

Quantification of Biogenic Amines

Check if the same lab product or an alternative is used in the 5 most similar protocols

Biogenic amines standards m ethylamine hydrochloride 99% (MA), ethylamine hydrochloride 98%(EA), dim ethylamine hydrochloride 99% (DMA), diethylamine hydrochloride 99% (DEA), propylamine hydrochloride 99% (PA), butylamine 99% (BA), 2-phenylethylamine hydrochloride 98% (PHA), tyramine hydrochloride 98% (TYR), tryptamine hydrochloride 99% (TRP), histamine dihydrochloride 99% (HIS), hexylamine 99%(HEA), isopentylamine 99% (isoPA), putrescine dihydrochloride 98% (PUT), cadaverine dihydrochloride 98% (CAD),spermidine trihydrochloride 99.5%(SPD), spermine tetrahydrochloride 99.5% (SPE), agmatine sulfate 98% (AGM) were obtained from Sigma Aldrich (St. Louis, MO, USA). The internal standard (IS) was 1.7-diamoheptane 98% (DAH) purchased from Sigma Aldrich (St. Louis, MO, USA). Formic acid (FA) was obtained from Merck (Darmstadt, Germany). Boric acid and sodium hydroxide were purchased from POCH (Gliwice, Poland). Acetonitrile (ACN) with LC-MS grade, ammonium formate and tosyl chloride (≥99%) were obtained from Sigma Aldrich (St. Louis, MO, USA). Nylon Captiva Econofilters (25 mm diameter, 0.2 µm pore size) were purchased from Agilent Technologies (Santa Clara, CA, USA). Ultrapure water was produced by the HLP5 system from Hydrolab (Wiślina, Poland).

Nalazek-Rudnicka K., Wojnowski W, & Wasik A. (2021). Occurrence and Levels of Biogenic Amines in Beers Produced by Different Methods. Foods, 10(12), 2902.

+ Open protocol

+ Expand

Synthesis of Functional Azide-Containing Monomers

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

Propargyloxylactic acid (5) was synthesized according to our previous report.^{31 (link)} The tosylate of triethylene glycol monomethyl ether was prepared following a previous report.³² 1-(2-azidoethoxy)-2-(methoxyethoxy) ethane (m3PEGN₃)³³ and 1-azidodecane (C₁₀H₂₁N₃)³⁴ were synthesized using literature procedures. Sodium azide, tosyl chloride (TsCl), p-toluenesulfonic acid monohydrate (TsOH), 4-tert-butylbenyl alcohol (TBBA), triethylene glycol monomethyl ether (m3PEG) and 1-bromo-decane were purchased from Sigma-Aldrich. l-Lactide (LA) was purchased from Sigma-Aldrich and recrystallized from ethyl acetate before use. Stannous octanoate (Sn(Oct)₂) was freshly distilled under vacuum and kept in dry box before use. THF and toluene were dried over sodium/benzophenone and distilled before use. The silica gel (60 Å porosity) for column chromatography was purchased from SiliCycle Inc. All other reagents and solvents were ACS grade and used as received unless specified.

Zhang Q., Ren H, & Baker G.L. (2015). Synthesis and click chemistry of a new class of biodegradable polylactide towards tunable thermo-responsive biomaterials. Polymer chemistry, 6(8), 1275-1285.

+ Open protocol

+ Expand

Determination of Biogenic Amines by LC-MS

Check if the same lab product or an alternative is used in the 5 most similar protocols

Seventeen biogenic amines: propylamine, di methylamine, diethylamine, methylamine, tryptamine, cadaverine, spermine, 2-phenylethylamine, tyramine, putrescine, histamine, butylamine, hexylamine, isopentylamine, isobutylamine, spermidine, agmatine, acetonitrile (LC–MS grade), and tosyl chloride (≥99%) were obtained from Sigma Aldrich (St. Louis, USA). Formic acid (FA) was purchased from Merck (Darmstadt, Germany). Boric acid and sodium hydroxide were purchased from POCH (Gliwice, Poland). Nylon Captiva Econofilters (25 mm diameter, 0.2 µm pore size) were purchased from Agilent Technologies (Santa Clara, USA). Ultrapure water was prepared using HLP₅ system from Hydrolab (Wiślina, Poland). Borate buffer was prepared by titrating 0.5 M boric acid solution with sodium hydroxide to the required pH value. Chemical structures of studied biogenic amines are shown in Fig. 4.Fig. 4

Chemical structures of biogenic amines under the study

Nalazek-Rudnicka K, & Wasik A. (2017). Development and validation of an LC–MS/MS method for the determination of biogenic amines in wines and beers. Monatshefte Fur Chemie, 148(9), 1685-1696.

+ Open protocol

+ Expand

Synthesis of Nanoparticles from Organometallic Precursors

Check if the same lab product or an alternative is used in the 5 most similar protocols

Ethylene (99.9%) and argon (99.999%) were purchased from Linde AG (Munich, Germany). Toluene (HPLC grade) was bought from Sigma-Aldrich Chemie GmbH (Munich, Germany), and degassed and stored over a molecular sieve. Butyloctylmagnesium (20 wt % in heptane) was purchased from Chemtura Europe GmbH (Frauenfeld, Switzerland). AgNO₃ (Fluka, 98%, Schwerte, Germany), oleylamine (ACROS organics, Geel, Belgium, C-18 content 80–90%), tetra-N-octylammonium bromide (ABCR, 98%), hydrogen tetrachloroaurate trihydrate (ABCR, Karlsruhe, Germany, 99.9%), and NdCl₃ (Fisher Scientific GmbH, Schwerte, Germany, 99.9%) were used as received. Tetrahydrofuran (Sigma-Aldrich, Munich, Germany) was distilled over CaH₂ and stored over a molecular sieve. Phenylmethanethiol, lithium pentamethylcyclopentadienide (>98%) N,N-dimethylformamide (DMF) (p.A.), sodium citrate tribasic dihydrate (99%), methanol (99.8%), sodium borohydride (96%), chloroform (p.A.), potassium hydroxide, aliquat 336, tosyl chloride (>98%), and hydrazine monohydrate (98%) were purchased from Sigma-Aldrich and used as received.

Wagner J., Peng W, & Vana P. (2018). Polyethylene-Grafted Gold and Silver Nanoparticles Using Catalyzed Chain Growth (CCG). Polymers, 10(4), 407.

+ Open protocol

+ Expand

Synthesis of Functionalized Lignin Polymers

Check if the same lab product or an alternative is used in the 5 most similar protocols

Sulfonated lignin, Tosyl chloride, 2-methyl oxazoline, 3-amino-1H-1,2,4 triazole was purchased from Sigma Aldrich, USA. All solvents were of analytical grade from Merck (India). Fetal bovine serum, Hank’s balanced salt solution (HBSS) and Dulbecco’s modified Eagle’s medium (DMEM)/F-12 were from Mediatech, Valley Park, MO, USA. Dulbecco’s Modified Eagle Media (DMEM-F12), Fetal bovine serum (FBS), Antimycotic antibiotic, L-glutamine, 0.05% trypsin-EDTA solution and Phosphate Buffered Saline (PBS) were purchased from high media, India.

Mahata D., Jana M., Jana A., Mukherjee A., Mondal N., Saha T., Sen S., Nando G.B., Mukhopadhyay C.K., Chakraborty R, & Mandal S.M. (2017). Lignin-graft-Polyoxazoline Conjugated Triazole a Novel Anti-Infective Ointment to Control Persistent Inflammation. Scientific Reports, 7, 46412.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!