Alanine transaminase

Manufactured by Randox

Sourced in United Kingdom

Alanine transaminase is a laboratory test used to measure the levels of the enzyme alanine transaminase in the blood. Alanine transaminase is primarily found in the liver and is involved in the metabolism of amino acids.

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Lab products found in correlation

Aspartate transaminase, by Randox (3 mentions) Bilirubin, by Randox (2 mentions) Urea, by Randox (1 mentions) Creatinine, by Randox (1 mentions) Alkaline phosphatase, by Randox (1 mentions) Total protein, by Randox (1 mentions) Gamma glutamyl transferase, by Randox (1 mentions)

3 protocols using alanine transaminase

Analysis of Medicinal Plant Compounds

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Fresh samples of the sclerotia of P. tuberregium were purchased from Mile 1 Market in Port Harcourt, Nigeria, while fresh leaves of C. aconitifolius (hospital too far) were collected from Farm Gardens in Aluu Community of Rivers State, Nigeria, and were duly identified as previously reported (Ikewuchi and Ikewuchi, 2009 , 2011 ; Ikewuchi et al., 2013a (link),b , 2014 (link), 2017 (link); Ifeanacho et al., 2019a (link),b , 2020 (link)). Ninety Wistar rats (weight 80–130 g) were obtained from the Animal House of the Department of Physiology, University of Port Harcourt, Nigeria. The alanine transaminase, aspartate transaminase, alkaline phosphatase, creatinine, and urea kits were the products of Randox Laboratories Ltd., County Antrim, UK.

Ikewuchi C.C., Ikewuchi J.C, & Ifeanacho M.O. (2021). Restoration of plasma kidney and liver biomarkers in doxorubicin-treated Wistar rats by aqueous extracts of Pleurotus tuberregium sclerotia and Cnidoscolus aconitifolius leaves. BioTechnologia, 102(3), 297-306.

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Hepatotoxicity Evaluation Protocol

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Acetaminophen, chloroform, and methanol used were obtained from Fam-lab Nigeria Limited, Akure, and Lixok-k chemicals, Akure, respectively. Alanine transaminase (ALT), aspartate transaminase (AST), gamma glutamyltransferase (GGT) and total protein, and bilirubin were obtained from Randox Laboratories Limited, UK.

Adetuyi B.O., Adebisi O.A., Adetuyi O.A., Ogunlana O.O., Toloyai P.E., Egbuna C., Uche C.Z., Khan J., Adumanya O.C, & Patrick-Iwuanyanwu K.C. (2022). Ficus exasperata Attenuates Acetaminophen-Induced Hepatic Damage via NF-κB Signaling Mechanism in Experimental Rat Model. BioMed Research International, 2022, 6032511.

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Biochemical Assays for Liver and Kidney Evaluation

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All chemicals and reagents were of analytical grade and were used as supplied. Assay kits for alkaline phosphate (ALP), aspartate transaminase (AST), alanine transaminase (ALT), creatinine (CREA), urea, albumin (ALB), and bilirubin (BIL) were products of Randox Laboratories Limited (Crumlin, UK).

Sulaiman F.A., Sulaiman F.A., Yusuf B.O., Muritala H., Adeyemi S.B., Omar S.A., Dosumu K.A., Adeoti Z.J., Adegbesan O.A., Busari B.O., Otohinoyi D.A., Rotimi D., Batiha G.E., & Adeyemı O.S. (2020). The GC-MS fingerprints of Nicotiana tabacum L. extract and propensity for renal impairment and modulation of serum triglycerides in Wistar rats. Journal of Pharmacy & Pharmacognosy Research, 8(1), 191-200.

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