3t magnetom tim trio mri

Participants were scanned pre-, mid-, and post-intervention. MR images were acquired using a 3T Magnetom Tim Trio MRI scanner system (Siemens Medical Systems, Erlangen) using a 32-channel radiofrequency head coil. T₁-weighted images were obtained using a 3D T₁-weighted magnetization prepared gradient-echo (MPRAGE) sequence. The multi-parameter mapping protocol used to acquire the MT maps comprised one static magnetic (B₀) gradient echo (GRE)-field map, one radiofrequency (RF) transmit field map (B₁), and three multi-echo 3D fast low angle shot (FLASH) scans (Helms et al., 2008b (link); Tabelow et al., 2019 (link)). Diffusion-weighted images were obtained with a single-shot diffusion-weighted spin-echo-refocused echo-planar imaging sequence. Further details regarding the acquisition parameters can be found in the Supplementary Material.

Magnetic resonance imaging (MRI) scans were acquired using a 3T Magnetom Tim Trio MRI scanner system (Siemens Medical Systems, Erlangen, Germany) using a 12-channel radiofrequency head coil. High-resolution anatomical images were collected using a T1-weighted 3D MPRAGE sequence (TR = 2500 ms, TE = 4.77 ms, TI = 1100 ms, acquisition matrix = 256 × 256 × 192, sagittal FOV = 256 mm, flip angle = 7°, voxel size = 1.0 mm × 1.0 mm × 1.0 mm).