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Architect hbeab

Manufactured by Abbott
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Sourced in Japan

The Architect HBeAb is a diagnostic instrument used for the detection and quantification of hepatitis B e antigen (HBeAg) in human serum or plasma samples. It utilizes chemiluminescent microparticle immunoassay (CMIA) technology to provide accurate and reliable results.

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Lab products found in correlation

Architect hbeag, by Abbott (2 mentions) Cobas taqman hbv test v2, by Roche (1 mentions) Architect hbsag qt assay kit, by Abbott (1 mentions) Architect hbsag qt, by Abbott (1 mentions)

2 protocols using architect hbeab

1

Comprehensive HBV Assessment Protocol

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Serum HBV-DNA levels were measured with COBAS TaqMan HBV Test v2.0 (Roche Diagnostics K.K., Tokyo, Japan); the lower limit of quantification was 20 IU/mL. Serum HBsAg levels were measured by chemiluminescence immunoassay using the Architect HBsAg QT assay kit (Abbott Japan Corp, Tokyo, Japan), and the HBeAg, anti-HBe and HBcrAg levels were measured by chemiluminescence enzyme immunoassay using the Architect HBeAg (Abbott Japan Corp,), Architect HBeAb (Abbott Japan Corp,) and Lumipulse HBcrAg (Fuji-Rebio, Tokyo, Japan) kits [12 (link)], respectively. The infecting HBV genotype was identified by enzyme-linked immunosorbent assay using monoclonal antibodies directed against type-specific epitopes in the preS2-region (Institute of Immunology, Tokyo, Japan).
Uchida Y., Nakao M., Yamada S., Tsuji S., Uemura H., Kouyama J.I., Naiki K., Sugawara K., Nakayama N., Imai Y., Tomiya T, & Mochida S. (2022). Superiority of tenofovir alafenamide fumarate over entecavir for serum HBsAg level reduction in patients with chronic HBV infection: A 144-week outcome study after switching of the nucleos(t)ide analog. PLoS ONE, 17(2), e0262764.
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2

Hepatitis B Virus Genome and Biomarker Analysis

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The HBV genome sequence of the HBc region at the vicinity region around amino acid at 97 was determined by direct sequencing, as reported previously, by using patient serum obtained at baseline.13 The HBV DNA titer was measured by COBAS AmpliPrep/COBAS TaqMan HBV Test v2.0 (Roche Diagnostics, Tokyo, Japan). The dynamic range of this assay is 2.1–9.0 log copies/mL. The titers of HBsAg (Architect HBsAg QT; Abbott Japan, Tokyo, Japan), HBeAg (Architect HBeAg; Abbott Japan), and anti-HBe (Architect HBeAb; Abbott Japan) were examined using chemiluminescence immunoassays. The lower detection limit of HBsAg is 0.05 IU/mL.39 (link)
Honda T., Yamada N., Murayama A., Shiina M., Aly H.H., Kato A., Ito T., Ishizu Y., Kuzuya T., Ishigami M., Murakami Y., Tanaka T., Moriishi K., Nishitsuji H., Shimotohno K., Ishikawa T., Fujishiro M., Muramatsu M., Wakita T, & Kato T. (2021). Amino Acid Polymorphism in Hepatitis B Virus Associated With Functional Cure. Cellular and Molecular Gastroenterology and Hepatology, 12(5), 1583-1598.
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