Martinos Center for Biomedical Imaging with a 3-axis gradient head coil in a 3
Tesla Siemens MRI System. A high-resolution T1-weighted structural image was
acquired by an isotropic multiecho MPRAGE pulse sequence for anatomic
localization of significant signal changes. Functional MRI images were acquired
using a gradient echo T2*-weighted pulse sequence [time repetition (TR)/time
echo (TE)=2000/30ms, flip angle (FA)=90°, field of view
(FOV)=192×192 mm, 48 AC-PC aligned slices, slice thickness = 3.0 mm with
0.6 mm inter-slice gap, 90 image volumes per slice, matrix size=96×96]
and a 32-channel multiarray coil. During the resting-state fMRI, which lasted
approximately nine minutes, participants were asked to keep their eyes open and
to blink normally while looking at a darkened screen and to not think about any
particular thing.