Eleven male wild-type mice (C57BL/6 J, 7–8 weeks) and 23 Tg2576 (APP KM670/671NL, 8 months old; Taconic, Rensselaer, NY) and 24 5XFAD (APP KM670/671NL [Swedish], APP I716V [Florida], APP V717I [London], PSEN1 M146L, PSEN1 L286V, 4 months old; Jackson Laboratory, Bar Harbor, ME) male mice on a hybrid C57BL/6 J background were utilised for the experiments. Animals were housed in individually ventilated cages with free access to food and water. The animal room was controlled with a 12 h light/dark cycle (lights on at 8:00 a.m.), and the temperature was maintained at 22–30 °C.
App v717i
Manufactured by Jackson ImmunoResearch
The APP V717I is a laboratory equipment product. It serves a core function, but a detailed description cannot be provided while maintaining an unbiased and factual approach without extrapolation.
Automatically generated - may contain errors
Lab products found in correlation
App km670 671nl, by Jackson ImmunoResearch (2 mentions)
App i716v, by Jackson ImmunoResearch (2 mentions)
Psen1 m146l, by Jackson ImmunoResearch (2 mentions)
Psen1 l286v, by Jackson ImmunoResearch (2 mentions)
App km670 671nl, by Taconic Biosciences (1 mentions)
Psen1 m146v, by Jackson ImmunoResearch (1 mentions)
Taup301l, by Jackson ImmunoResearch (1 mentions)
2 protocols using app v717i
1
Transgenic Mouse Models of Alzheimer's
2
Transgenic Mouse Models for Alzheimer's
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AD model 5xFAD mice (APP KM670/671NL [Swedish], APP I716V [Florida], APP V717I [London], PSEN1 M146L [A>C], PSEN1 L286V) and 3xTg-AD mice (APP Swedish, tauP301L, PSEN1 M146V) were purchased from Jackson Laboratory. All animal experiments and procedures were approved by the Institutional Animal Care and Use Committee of Sungkyunkwan University (2018-01-01-1).
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