D saccharic acid 1

Manufactured by Merck Group

Sourced in United States

D-Saccharic acid is a chemical compound primarily used as a laboratory reagent. It is a sugar acid derived from glucose. The core function of D-Saccharic acid is to serve as a chemical intermediate and analytical standard in various research and testing applications.

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Lab products found in correlation

4 lactone, by Merck Group (2 mentions) Udpga, by Merck Group (1 mentions) Transcutol, by Gattefosse (1 mentions) Alamethicin, by Merck Group (1 mentions) Tween 80, by Nanjing Chemical Reagent (1 mentions) Oleic acid, by Nanjing Chemical Reagent (1 mentions) Hplc grade acetonitrile, by Merck Group (1 mentions) Cremophor rh40, by BASF (1 mentions) Cremophor el, by BASF (1 mentions) Labrasol, by Gattefosse (1 mentions) Capryol 90, by Gattefosse (1 mentions) Peceol, by Gattefosse (1 mentions) Solutol hs 15, by BASF (1 mentions) Labrafil m 1944 cs, by Gattefosse (1 mentions) Labrafac lipophile wl 1349, by Gattefosse (1 mentions) Aryl sulfatase, by Merck Group (1 mentions) Ultima flo m permafluor e, by PerkinElmer (1 mentions)

Close spelling variants of this product

D-saccharic acid 1,4-lactone D-saccharic acid 1,4-lactone monohydrate D-saccharic-1

2 protocols using d saccharic acid 1

Comprehensive Characterization of Lipid Excipients

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NOR (purity >98%) was purchased from Chengdu Chroma Biotechnology Co., Ltd. (Chengdu, People's Republic of China). soybean phospholipid (95% phosphatidylcholine) was donated by Shanghai Avet Pharmaceutical Technology Co., Ltd. (Shanghai, People's Republic of China). Labrafac Lipophile WL1349, Labrafil M 1944 CS, Peceol, Capryol 90, Lauroylycol 90, Labrasol, and Transcutol HP (analytical purity) were kindly supplied by Gattefossé (Shanghai, People's Republic of China). Cremophor EL, Cremophor RH 40, and Solutol HS 15 (analytical purity) were donated by BASF (Shanghai, People's Republic of China). Oleic acid and tween 80 (analytical purity) were purchased from Nanjing Chemical Reagent Co., Ltd. (Nanjing, People's Republic of China). Ethyl oleate and MgCl₂ (analytical purity) were obtained from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, People's Republic of China). UDPGA (purity >93%), D-Saccharic acid 1, 4-lactone (purity >98%), and alamethicin (purity >98%) were purchased from Sigma-Aldrich (St. Louis, MO, USA). BCA Protein Assay Kit was purchased from Nanjing Jiancheng Bioengineering Insitute (Nanjing, People's Republic of China). Sinomenine (purity >98%, internal standard) was purchased from Nanjing Jingzhu Bio-technology Co., Ltd. HPLC-grade acetonitrile was purchased from Merck (Darmstadt, German). All other chemicals and solvents were of analytical purity.

Zhang J., Wen X., Dai Y, & Xia Y. (2019). Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex. International Journal of Nanomedicine, 14, 7095-7106.

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Radiolabeled TBBPA Characterization

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[¹⁴C]-radiolabeled TBBPA (uniform ring-labeled; Figure 1), previously described by Kuester et al (2007) (link) was generously provided by I. Glenn Sipes at the University of Arizona (Tucson, AZ) for use in the present study. Reversed-phase HPLC fractionation (described below) was used to acquire a radiochemical purity of >98% (specific activity = 90.3 mCi/mmol). [¹⁴C]-TBBPA was reconstituted in dimethyl sulfoxide. Chemical purity was determined to be >98% as compared to a TBBPA reference standard (Sigma-Aldrich; St. Louis, MO). Scintillation cocktails were obtained from MP Biomedicals (Ecolume; Santa Ana, CA) or Perkin-Elmer (Ultima-Flo M & PermaFluor E+; Torrance, CA). Cremophore EL®, dimethylsulfoxide, β-glucuronidase (EC 3.2.1.31, Type B-10), ammonium acetate, D-saccharic acid 1, 4-lactone, and aryl sulfatase were purchased from Sigma-Aldrich. All other reagents used in these studies were high performance liquid chromatography (HPLC) or analytical grade.

Knudsen G.A., Sanders J.M., Sadik A.M, & Birnbaum L.S. (2014). Disposition and kinetics of tetrabromobisphenol A in female Wistar Han rats. Toxicology Reports, 1, 214-223.

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