Cardiac magnetic resonance imaging was performed using a 1.5-T system (Philips Achieva 1.5 Tesla, operating release 2.6 level 3, Philips Healthcare, Netherlands). All CMR exams were reviewed by a single experienced level-3 certified cardiologist who was blinded to the clinical data and myocardial phenotype of the patients. Myocardial fibrosis was quantified using validated software (CVI42, Circle, Canada) as previously described by our group (20 (link)). We set limits for myocardial fibrosis at ≥ 6 SD from the normal myocardium in accordance with published criteria for the assessment of myocardial fibrosis in hypertrophic cardiomyopathy (21 (link), 22 (link)).
Achieva 1.5 tesla
Manufactured by Philips
Sourced in Netherlands
The Achieva 1.5 Tesla is a magnetic resonance imaging (MRI) system manufactured by Philips. It operates at a field strength of 1.5 Tesla, which is a common field strength used in clinical MRI applications. The Achieva 1.5 Tesla is designed to provide high-quality medical imaging for diagnostic purposes.
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Lab products found in correlation
4 protocols using achieva 1.5 tesla
1
Cardiac MRI Fibrosis Quantification
2
Cardiac MRI Protocol for Fibrosis Assessment
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All CMR exams were performed using the same system (Achieva 1.5 Tesla, Philips
Healthcare, Cleveland, OH). A five-element cardiac phased-array coil was used
for signal reception and cardiac synchronization was performed using a vector
electrocardiogram. Cine-CMR images were acquired in 8-10 contiguous short-axis
slices from the level of the mitral valve annulus through the LV apex using a
commercially available steady-state free precession pulse sequence. Technical
parameters were as follows: TR/TE (ms): 3.5/1.8; flip angle: 60°; section
thickness: 8 mm; matrix: 144 x 157; field of view: 320 mm; voxel size: 2.2 x 2.0
mm; and number of phases: 30. For detection of the presence, extent and location
of fibrosis, a breath-hold, T1-weighted, contrast-enhanced inversion-recovery
segmented gradient echo sequence (TR/TE (ms): 4.8/2.3; flip angle: 25°; section
thickness: 10 mm; matrix: 184 x 154; field of view: 320 mm; voxel size: 1.75 x
1.95 mm) was used. These LGE-CMR images were acquired 10 minutes after
intravenous administration of 0.2 mmol/kg of a commercially available gadolinium
chelate of diethylenetriamine pentaacetic acid bismethoxyethylamide
(gadoversetamide, Mallinckrodt, St. Louis, USA), using identical long- and
short-axis planes to the cine images, except for the most apical short-axis
slice, which was excluded because it can be affected by partial-volume
effects.
Healthcare, Cleveland, OH). A five-element cardiac phased-array coil was used
for signal reception and cardiac synchronization was performed using a vector
electrocardiogram. Cine-CMR images were acquired in 8-10 contiguous short-axis
slices from the level of the mitral valve annulus through the LV apex using a
commercially available steady-state free precession pulse sequence. Technical
parameters were as follows: TR/TE (ms): 3.5/1.8; flip angle: 60°; section
thickness: 8 mm; matrix: 144 x 157; field of view: 320 mm; voxel size: 2.2 x 2.0
mm; and number of phases: 30. For detection of the presence, extent and location
of fibrosis, a breath-hold, T1-weighted, contrast-enhanced inversion-recovery
segmented gradient echo sequence (TR/TE (ms): 4.8/2.3; flip angle: 25°; section
thickness: 10 mm; matrix: 184 x 154; field of view: 320 mm; voxel size: 1.75 x
1.95 mm) was used. These LGE-CMR images were acquired 10 minutes after
intravenous administration of 0.2 mmol/kg of a commercially available gadolinium
chelate of diethylenetriamine pentaacetic acid bismethoxyethylamide
(gadoversetamide, Mallinckrodt, St. Louis, USA), using identical long- and
short-axis planes to the cine images, except for the most apical short-axis
slice, which was excluded because it can be affected by partial-volume
effects.
3
Lumbosacral MRI and MRM Imaging Parameters
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All cases were examined using the same MRI device (Philips Achieva 1.5 Tesla, Netherland, 2010). During lumbosacral evaluation, MRI and MRM were performed using the following imaging parameters:
(1) Sagittal T1-weighted images: turbo spin echo (TSE) echo time (TE)=8 msec and repetition time (TR)=500 msec.
(2) Sagittal T2-weighted images: TSE TE=100 msec and TR=4,000 msec.
(3) Axial T2-weighted images: TE=120 msec and TR=4,000 msec.
(4) MRM (heavily T2-weighted images): TE=1,000 msec and TR=8,000 msec.
(1) Sagittal T1-weighted images: turbo spin echo (TSE) echo time (TE)=8 msec and repetition time (TR)=500 msec.
(2) Sagittal T2-weighted images: TSE TE=100 msec and TR=4,000 msec.
(3) Axial T2-weighted images: TE=120 msec and TR=4,000 msec.
(4) MRM (heavily T2-weighted images): TE=1,000 msec and TR=8,000 msec.
4
Neonatal Brain MRI for HIE Assessment
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All infants included in the study underwent brain MRI at a median age of 6 days of life. The MRI equipment was a Philips Achieva 1.5 Tesla (Philips Healthcare, Best, Netherlands). The MRI sequence protocol included 3D gradient echo T1-weighted images, gradient echo T2-weighted images, turbo spin echo T2-weighted images, and echo planar diffusion-weighted images. MRI scans were blindly reviewed by an experienced pediatric neuroradiologist, and damage was graded according to the score proposed by Barkovich AJ et al. [19 (link)]. Patients were scored according to damage of basal ganglia, cortical watershed areas, and sum of basal ganglia and watershed damage, and grouped as: “no HIE” if their cumulative score was 0, or “HIE” if their cumulative score was >0.
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