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Salidroside

Manufactured by MedChemExpress
Sourced in China

Salidroside is a chemical compound naturally found in the plant Rhodiola rosea. It is a white crystalline powder that is soluble in water and various organic solvents. Salidroside is commonly used as a research reagent and standard in analytical applications.

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4 protocols using salidroside

1

Salidroside Modulates Platelet Activation

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Salidroside was purchased from MedChemExpress (Monmouth Junction, NJ, USA) with a purity ≥ 98%. Collagen-related peptide (CRP) was prepared as previously described [56 (link)]. Thrombin (≥ 10 NIH units/vial) were from Chrono-log Corporation (Havertown, PA, USA). FITC-conjugated mouse anti-human CD41a and PAC-1 antibody were from BD Biosciences (San Jose, CA, USA) and BECTON DICKINSON (San Jose, CA, USA) respectively. PE-conjugated anti-human/mouse CD62p (P-Selectin) and anti-human Glycoprotein VI purified antibody were purchased from eBioscience (San Diego, CA, USA). FITC-conjugated anti-CD42b antibody was from Abcam (Cambridge, MA, USA). FITC-conjugated goat anti-mouse IgG was purchased from ZSGB-BIO (Beijing, China). β-actin antibody and anti-rabbit IgG (HRP-linked) antibody were purchased from Cell Signaling Technology (Danvers, MA, USA). SB216763 (GSK-3β inhibitor) was purchased from ApexBio Technology.
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2

Salidroside Activates AMPK Signaling

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Salidroside (MedChemExpress, Product No. 10338-51-9, purity >99.99%, molecular weight 300.30) is ordered commercially. Rabbit anti-p-AMPK (Thr 172) (1:1000, #2535, Cell Signaling Technology [CST], U.S.A.), rabbit anti-AMPK (1:1000, #5831, CST, U.S.A.) and TXNIP (1:1000, #14715, CST, U.S.A.).
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3

Mitochondrial Apoptosis and Energy Regulation

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Reagents Salidroside (#HY-N0109) and Compound C (#HY-13418A) were purchased from MedChemExpress (China); DHT (#S4757) was purchased from Selleck (China), and AMPK siRNA (#sc45312) and negative control siRNA (#sc-37007) were purchased from Santa Cruz Biotech. Nrf2 siRNA and RNATransMate (#E607402) was purchased from Sangon Biotech (China). The nuclear and cytoplasmic extraction reagent (#78833) was obtained from ThermoFisher (USA). The Mitochondrial Membrane Potential Assay Kit with JC-1 (#C2006), Annexin V-PE Apoptosis Detection Kit (#C1065L), and Cell Counting Kit-8 (CCK-8; #C0037) were obtained from Beyotime Biotechnology (China).
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4

Mitochondrial Apoptosis and Energy Regulation

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Reagents Salidroside (#HY-N0109) and Compound C (#HY-13418A) were purchased from MedChemExpress (China); DHT (#S4757) was purchased from Selleck (China), and AMPK siRNA (#sc45312) and negative control siRNA (#sc-37007) were purchased from Santa Cruz Biotech. Nrf2 siRNA and RNATransMate (#E607402) was purchased from Sangon Biotech (China). The nuclear and cytoplasmic extraction reagent (#78833) was obtained from ThermoFisher (USA). The Mitochondrial Membrane Potential Assay Kit with JC-1 (#C2006), Annexin V-PE Apoptosis Detection Kit (#C1065L), and Cell Counting Kit-8 (CCK-8; #C0037) were obtained from Beyotime Biotechnology (China).
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