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N methyl 2 pyrrolidone

Manufactured by Iris Biotech
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Sourced in Germany

N-Methyl-2-pyrrolidone is a colorless, odorless, and highly polar organic solvent. It is commonly used as a processing aid in various industrial applications.

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Lab products found in correlation

N n diisopropylethylamine, by Merck Group (3 mentions) N n dimethylformamide (dmf), by Merck Group (3 mentions) Bis boc aminooxy acetic acid, by Merck Group (2 mentions) Ethyl cyano hydroxyimino acetate, by Merck Group (2 mentions) Rink amide mbha resin, by Merck Group (2 mentions) Triethylsilane, by Merck Group (2 mentions) 2 1h benzotriazol 1 yl 1 1 3 3 tetramethyluronium hexafluorophosphate hbtu, by Merck Group (1 mentions) Methanol, by Merck Group (1 mentions) Dichloromethane, by Merck Group (1 mentions) Triethylamine, by Merck Group (1 mentions) Piperidine, by Merck Group (1 mentions) Dichloromethane dcm, by Biosolve (1 mentions) Acetonitrile, by Carlo Erba (1 mentions)

3 protocols using n methyl 2 pyrrolidone

1

Solid-Phase Peptide Synthesis Protocol

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Merck Millipore (Burlington, MA, United States) provided acetic acid, acetone, acetonitrile, Fmoc-protected amino acids, Bis-Boc-aminooxy acetic acid (Aoa), dichloromethane (DCM), N,N-diisopropylethylamine (DIPEA), N,N-dimethylformamide (DMF), ethyl cyano(hydroxyimino)acetate (Oxyma Pure), methanol, Rink amide MBHA resin, triethylamine (TEA), triethylsilane (TES), and 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluoro phosphate (HBTU). Biosolve (Valkenswaard, Holland) provided diethyl ether and trifluoroacetic acid (TFA). PanReac Appli-Chem (Darmstadt, Germany) provided 2-propanol for HPLC (aldehyde and ketone free), while Carlo Erba (Milan, Italy) provided ethanol. Iris Biotech GmbH (Marktredwitz, Germany) provided N-Methyl-2-pyrrolidone (NMP).
Cassari L., Zamuner A., Messina G.M., Marsotto M., Chang H.C., Coward T., Battocchio C., Iucci G., Marletta G., Di Silvio L, & Dettin M. (2023). Strategies for the Covalent Anchoring of a BMP-2-Mimetic Peptide to PEEK Surface for Bone Tissue Engineering. Materials, 16(10), 3869.
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2

Solid-Phase Peptide Synthesis Methodology

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Acetic acid, acetone, acetonitrile, Fmoc protected Amino acids, Bis-Boc-aminooxy acetic acid (Aoa), Dichloromethane (DCM), N,N-Diisopropylethylamine (DIPEA), N,N-dimethylformamide (DMF), Ethyl cyano(hydroxyimino)acetate (Oxyma Pure), Methanol, Rink-Amide MBHA resin, Triethylamine (TEA), Triethylsilane (TES), 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluoro phosphate (HBTU) were purchased from Merck Millipore (Burlington, MA, USA). Diethyl ether, Trifluoroacetin acid (TFA) were purchased from Biosolve (Valkenswaard, Holland). 2-Proponal for HPLC (aldehyde and ketone free) was purchased from PanReac AppliChem (Darmstadt, Germany). Ethanol was purchased from Carlo Erba (Milan, Italy). N-Methyl-2-pyrrolidone (NMP) was purchased from Iris Biotech GmbH (Marktredwitz, Germany).
Cassari L., Zamuner A., Messina G.M., Marsotto M., Chen H., Gonnella G., Coward T., Battocchio C., Huang J., Iucci G., Marletta G., Di Silvio L, & Dettin M. (2023). Bioactive PEEK: Surface Enrichment of Vitronectin-Derived Adhesive Peptides. Biomolecules, 13(2), 246.
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3

Solid-Phase Peptide Synthesis Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
The solid support resin Rink Amide MBHA, the Fmoc protected amino acids, the coupling reagents 2-(1H - Benzotriazole-1-yl) −1,1,3,3-tetramethyluronium hexafluorophosphate (HBTU), ethyl cyano(hydroxyimino)acetate (oxyma pure), N,N-diisopropylethylamine (DIEA), triethylsilane (TES), N,N-dimethylformamide (DMF) and piperidine were from 10.13039/100009945Merck KGaA, (Darmstadt, Germany). Trifluoroacetic acid (TFA), diethyl ether and dichloromethane (DCM) were from Biosolve (Leenderweg, Valkenswaard, Netherlands). Acetonitrile was from Carlo Erba (Milan, Italy). N-methyl-2-pyrrolidone (NMP) was purchased by Iris Biotech GmbH (Halle, Germany).
Stocco E., Barbon S., Faccio D., Petrelli L., Incendi D., Zamuner A., De Rose E., Confalonieri M., Tolomei F., Todros S., Tiengo C., Macchi V., Dettin M., De Caro R, & Porzionato A. (2023). Development and preclinical evaluation of bioactive nerve conduits for peripheral nerve regeneration: A comparative study. Materials Today Bio, 22, 100761.
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