HCV antibodies were detected using a third-generation enzyme immunoassay EIA 3.0 (Murex anti-HCV version 4.0; Abbott, Kyalami, South Africa). All reactive samples were retested in duplicate using the same EIA 3.0 assay. The level of reactivity in the EIA was calculated from two or more of the three test results [13 (link)]. The signal to cut-off ratio recommended by the Centers for Disease Control and Prevention (CDC) was used to define a positive HCV EIA test. An anti-HCV positive test was defined as a positive test result from both tests [14 (link)].
Murex anti hcv version 4
Manufactured by Abbott
Sourced in Germany
The Murex anti-HCV version 4.0 is a laboratory equipment product used for the detection of hepatitis C virus (HCV) antibodies in human serum or plasma samples. The core function of this product is to provide a diagnostic tool for the screening and identification of HCV infection.
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Lab products found in correlation
2 protocols using murex anti hcv version 4
1
HCV Antibody Detection Using EIA
2
Serological Screening Protocols for Donated Blood
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Laboratory testing was performed at the Serology Division of the Fundação Pró-São Paulo Hemocentro de São Paulo following usual blood bank procedures for HBV surface antigen, HBV core antibody, syphilis, anti-HCV, anti-HTLV-1/2, Chagas disease, and anti-HIV-1 and -2. Serologic reactive units were discarded according to institution policy.14 (link) Donors who presented any positive screening test results were contacted to collect another sample.
The Enzygnost HBsAg 5.0 (Siemens, Marburg, Germany) and Enzygnost Anti-HBc monoclonal (Siemens, Marburg, Germany) tests were used for HBV screening and confirmatory tests and the Murex anti-HCV version 4.0 (Abbott, South Africa) test was used for HCV screening. An immunoblot (CHIRON RIBA HCV 3.0 S/A, Emeryville, USA) was used for the HCV confirmatory test.
The Enzygnost HBsAg 5.0 (Siemens, Marburg, Germany) and Enzygnost Anti-HBc monoclonal (Siemens, Marburg, Germany) tests were used for HBV screening and confirmatory tests and the Murex anti-HCV version 4.0 (Abbott, South Africa) test was used for HCV screening. An immunoblot (CHIRON RIBA HCV 3.0 S/A, Emeryville, USA) was used for the HCV confirmatory test.
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