Skylight

Manufactured by Philips

Sourced in United Kingdom

Skylight is a laboratory equipment product from Philips. It serves as a lighting solution for laboratory environments, providing illumination to support various scientific activities and tasks.

Automatically generated - may contain errors

Lab products found in correlation

Prism xp2000, by Philips (3 mentions) Discovery vct pet ct scanner, by GE Healthcare (1 mentions) 123i mibg, by GE Healthcare (1 mentions) Carto 3 system, by Johnson & Johnson (1 mentions) Autospect plus, by Philips (1 mentions)

Close spelling variants of this product

Skylight gamma camera

8 protocols using skylight

Lung Distribution of Surfactant in Piglets

Check if the same lab product or an alternative is used in the 5 most similar protocols

Piglets were placed prone in a gamma camera (Philips Skylight, Philips AB, Stockholm, Sweden) with dual heads, simultaneously acquiring one anterior and one posterior image. After a 3-min exposure, 25 MBq of ^99mTc-macroaggregated albumin (Tc-MAA, TechneScan LyoMAA, Covidien Sverige AB, Solna, Sweden) was injected i.v., and a second exposure made. The ^99mTc-MAA is trapped in the lung capillaries and is used to outline the lungs and to do internal calibration as earlier described.^{14 (link)} Deposition at various regions of interest was calculated from the mean of the anterior and posterior images and presented as a percentage of the total atomized or instilled surfactant dose.
At the end of the study, i.e., after the gamma scintigraphy examination, the piglets were killed using an excess dose of pentobarbital, fentanyl, and potassium.

Nord A., Linner R., Milesi I., Zannin E., di Castri M., Bianco F., Dellacá R.L., Cunha-Goncalves D, & Perez-de-Sa V. (2019). A novel delivery system for supraglottic atomization allows increased lung deposition rates of pulmonary surfactant in newborn piglets. Pediatric Research, 87(6), 1019-1024.

+ Open protocol

+ Expand

Multimodal Imaging for Bone Assessment

Check if the same lab product or an alternative is used in the 5 most similar protocols

PET/CT data were obtained by a Discovery VCT PET/CT scanner (GE Healthcare). All patients received an injection of 3 MBq NaF per kg body weight after having fasted for 6 h. Image acquisition started approximately 60 min after tracer injection. A diagnostic contrast-enhanced CT scan (64-slice helical, 120 kV, “smart mA” maximum 400 mA) was obtained from the base of the skull to the mid-thigh. The CT slice thickness used in the analysis was 3.75 mm. A PET scan with an acquisition time of 2.5 min per bed position was obtained from the same region.
Whole-body planar bone scans with anterior and posterior views were acquired using a dual head ɣ camera (Skylight or PRISM XP2000, Philips Medical, Surrey) with LEHR collimator, energy window 140 keV ±20%, matrix 256×1024, and scan speed 14 cm/min. All patients received 600 MBq Tc-99m HDP and imaging acquisition was performed 3 h postinjection.

Lindgren Belal S., Sadik M., Kaboteh R., Hasani N., Enqvist O., Svärm L., Kahl F., Simonsen J., Poulsen M.H., Ohlsson M., Høilund-Carlsen P.F., Edenbrandt L, & Trägårdh E. (2017). 3D skeletal uptake of 18F sodium fluoride in PET/CT images is associated with overall survival in patients with prostate cancer. EJNMMI Research, 7, 15.

+ Open protocol

+ Expand

Whole-body Tc-99m-DPD Imaging Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

The patients were injected with 700 MBq (0.019 Ci) Technetium-99m-3,3-disphosphono-1,2-propanodicarboxylic acid (Tc-99m-DPD) three to four hours prior to whole-body imaging. In the waiting period, the patients were asked to drink approximately 1 liter of clear liquids. The scan was performed on a Skylight or PRISM XP2000 gamma camera (Philips Medical, Surrey, UK) with the following parameters: LEHR collimator, energy window 140 keV ± 20%, matrix 256 x 1024, scan speed 14 cm/min.

Hansen J.A., Naghavi-Behzad M., Gerke O., Baun C., Falch K., Duvnjak S., Alavi A., Høilund-Carlsen P.F, & Hildebrandt M.G. (2021). Diagnosis of bone metastases in breast cancer: Lesion-based sensitivity of dual-time-point FDG-PET/CT compared to low-dose CT and bone scintigraphy. PLoS ONE, 16(11), e0260066.

+ Open protocol

+ Expand

Planar Whole-Body Bone Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

Whole-body planar imaging in anterior and posterior positions was acquired 3 hours after injection of 600 MBq ^99mTc-hydroxymethylene diphosphonate using a dual head gamma camera (PRISM XP2000 or Skylight; Philips Medical, UK; with a low-energy high-resolution (LEHR) collimator, energy window of 140 keV ± 20%, matrix of 256 × 1024, and scan speed of 14 cm/min).

Mortensen M.A., Poulsen M.H., Gerke O., Jakobsen J.S., Høilund-Carlsen P.F, & Lund L. (2019). 18F-Fluoromethylcholine-positron emission tomography/computed tomography for diagnosing bone and lymph node metastases in patients with intermediate- or high-risk prostate cancer. Prostate International, 7(3), 119-123.

+ Open protocol

+ Expand

Quantifying Tumor Uptake of 166HoMS

Check if the same lab product or an alternative is used in the 5 most similar protocols

We assessed local ¹⁶⁶HoMS deposition in the tumor and possible unintended spread immediately after treatment using anterior-posterior and lateral planar gamma scintigraphy (Orbiter 37, Siemens Medical Systems, Illinois, USA; SKYLight, Philips Medical Systems). A medium-energy general-purpose collimator was used with energy windows set to 80.6 keV ± 7.5% for the ¹⁶⁶Ho photopeak and 118.0 keV ± 6.0% for correction for down-scattered high-energy photons, as previously described (38 (link)).

Morsink N.C., Nijsen J.F., Grinwis G.C., Hesselink J.W., Kirpensteijn J, & van Nimwegen S.A. (2022). Intratumoral injection of holmium-166 microspheres as neoadjuvant therapy of soft tissue sarcomas in dogs. Frontiers in Veterinary Science, 9, 1015248.

+ Open protocol

+ Expand

In-vivo Cardiac Perfusion Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

Four weeks after gene transfer, 99 mTc-sestamibi of 1 MBq (10 mCi) per kilogram was delivered to the animals. After 40 min, the heart images were collected with a dual-head γ camera (Skylight, Philips) in step-and-shoot mode. Then, 64 images (64×64 matrix) were acquired, 40 sec each and throughout a 180° arc. The images were reconstructed along the short, horizontal long, and vertical long axes of the heart. Quantitative analysis of perfusion defects was performed according to the AHA procedural guidelines for myocardial perfusion imaging in nuclear cardiology (12 (link)).

Lu W., Xie J., Gu R, & Xu B. (2017). Expression of integrin-linked kinase improves cardiac function in a swine model of myocardial infarction. Experimental and Therapeutic Medicine, 13(5), 1868-1874.

+ Open protocol

+ Expand

3D Mapping of Cardiac Innervation

Check if the same lab product or an alternative is used in the 5 most similar protocols

Preprocedural 123 I-MIBG SPECT images were obtained before VT ablation. Patients were administered 370 MBq (10 mCi) of 123 I-MIBG (GE Healthcare) intravenously. SPECT imaging of the chest was performed using a dual-head g-camera (SKYLight; Philips) 4 h after injection, with a minimum of 30 projections per head, 20-30 s/projection, and a 64 • 64 matrix. Camera heads were equipped with low-energy, high-resolution collimators, and all acquisitions were performed with a 20% energy window centered at the 159-keV photopeak of 123 I.
3D 123 I-MIBG Cardiac Map Reconstruction 3D reconstructions of myocardial innervation were created using Amira 5.4.2 software (Visage Imaging). On each 2-dimensional 123 I-MIBG SPECT slice, areas of abnormally innervated myocardium (,50% tracer uptake) were determined visually by 2 masked, experienced cardiac nuclear medicine physicians with previously demonstrated intraobserver or interobserver variability of less than 10% (8) . From the sequential 2-dimensional datasets, individual 3D innervation maps were created for each of the patients in the Amira environment (Figs. 1C and1D). Right ventricle (RV) reconstruction was performed to correct for rotational errors during registration. The datasets were then converted to CARTO 3 System (Biosense Webster) readable mesh files using custom-made software (7) .

Imanli H., Ume K.L., Jeudy J., Bob-Manuel T., Smith M.F., Chen W., Abdulghani M., Ghzally Y., Mahat J.B., Itah R., Restrepo A., See V.Y., Shorofsky S., Dilsizian V, & Dickfeld T. (2019). Ventricular Tachycardia (VT) Substrate Characteristics: Insights from Multimodality Structural and Functional Imaging of the VT Substrate Using Cardiac MRI Scar, ¹²³I-Metaiodobenzylguanidine SPECT Innervation, and Bipolar Voltage. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 60(1).

+ Open protocol

+ Expand

Ex-vivo SPECT Myocardial Perfusion Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

ex-vivo MPS was performed approximately 8–10 h after intravenous injection of a 1000 MBq dose of ^99mTc-tetrofosmin using a dual head camera (Philips SKYlight, Best, the Netherlands) and a vertex high resolution collimator (ADAC Vertex, Milpitas, CA, USA) at 32 projections (40 s per projection) with a 64 × 64 matrix yielding a digital resolution of 4.24 mm isotropic voxels. Iterative reconstruction using maximum likelihood expectation maximization (MLEM) was performed with a low resolution Butterworth filter with a cut-off frequency set to 0.6 of Nyquist and order 5.0. No attenuation or scatter correction was applied. Finally, a short-axis image stack was reconstructed using commercially available software (AutoSPECT Plus, Pegasys software version 5.01, Philips, Best, The Netherlands).

Nordlund D., Kanski M., Jablonowski R., Koul S., Erlinge D., Carlsson M., Engblom H., Aletras A.H, & Arheden H. (2017). Experimental validation of contrast-enhanced SSFP cine CMR for quantification of myocardium at risk in acute myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 19, 12.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!