Asipro vw software

Manufactured by Siemens

ASIPro VW is a software solution developed by Siemens for the analysis and simulation of industrial processes. The software provides a platform for modeling, optimizing, and monitoring various industrial applications, enabling users to make informed decisions and improve operational efficiency.

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Lab products found in correlation

Inveon pet scanner, by Siemens (5 mentions)

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ASIPro software ASIPro

5 protocols using asipro vw software

PET Imaging of Neurological Targets in Rats

Cited 3 times

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The general procedure
for PET studies was described previously^{35 (link),41 (link)} with minor modification in this work. Briefly, PET scans were carried
out with an Inveon PET scanner (Siemens Medical Solutions, Knoxville,
TN). Sprague–Dawley rats were kept under anesthesia using 1–2%
(v/v) isoflurane during the scan. The radiotracer (ca. 0.5 mCi/150
μL) was injected into the tail vein via a preinstalled catheter.
A dynamic scan in the three-dimensional (3D) list mode was acquired
for 60 min. For pretreatment studies, a solution of PF06447475 (3
mg/kg) in 300 μL saline containing 10% ethanol and 5% Tween
80 was injected via the pre-embedded tail vein catheter at 30 min
prior to tracer injection. As we previously reported,^{40 (link)−42 (link)} the PET dynamic images were reconstructed using ASIPro VW software
(Analysis Tools and System Setup/Diagnostics Tool, Siemens Medical
Solutions). Volumes of interest, including the hippocampus, cortex,
cerebellum, striatum, and thalamus, were placed using ASIPro software.
The radioactivity was decay-corrected and expressed as the standard
uptake value: SUV = (radioactivity per mL tissue/injected radioactivity)
× body weight.

Chen Z., Chen J., Mori W., Yi Y., Rong J., Li Y., Leon E.R., Shao T., Song Z., Yamasaki T., Ishii H., Zhang Y., Kokufuta T., Hu K., Xie L., Josephson L., Van R., Shao Y., Factor S., Zhang M.R, & Liang S.H. (2024). Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2). Journal of Medicinal Chemistry, 67(4), 2559-2569.

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Quantitative PET Imaging of Neurochemical Targets

Cited 1 time

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PET scans were acquired by an Inveon PET scanner (Siemens Medical Solutions, Knoxville, TN, USA). Sprague-Dawley rats were kept under anesthesia with 1–2% (v/v) isoflurane during the scan. The radiotracer (ca. 1 mCi/150–200 µL) was injected via a preinstalled catheter via tail vein. A dynamic scan in 3D list mode was acquired for 60 min. For pretreatment studies, QCA (1 mg/kg) pre-dissolved in 300 µL saline containing 10% ethanol and 5% Tween^® 80 was injected at 30 min via the tail vein catheter before the injection of [¹¹C]QCA.
As we previously reported,^{78 (link),79 (link)} the PET dynamic images were reconstructed using ASIPro VW software (Analysis Tools and System Setup/Diagnostics Tool, Siemens Medical Solutions). Volumes of interest, including the whole brain, cerebral cortex, cerebellum, striatum, thalamus and pons were placed using ASIPro software. The radioactivity was decay-corrected and expressed as the standardized uptake value. SUV = (radioactivity per mL tissue/injected radioactivity) × body weight.

Zhang X., Kumata K., Yamasaki T., Cheng R., Hatori A., Ma L., Zhang Y., Xie L., Wang L., Kang H.J., Sheffler D.J., Cosford N.D., Zhang M.R, & Liang S.H. (2017). Synthesis and preliminary studies of a novel negative allosteric modulator [11C]QCA for imaging of metabotropic glutamate receptor 2. ACS chemical neuroscience, 8(9), 1937-1948.

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PET Imaging of Cannabinoid Receptor 1

Cited 3 times

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PET scans were acquired by an Inveon PET scanner (Siemens Medical Solutions, Knoxville, TN, USA). Sprague-Dawley rats were kept under anesthesia with 1–2% (v/v) isoflurane during the scan. The radiotracer (ca. 1 mCi/150–200 μL) was injected via a preinstalled catheter via tail vein. A dynamic scan in 3D list mode was acquired for 90 min. For pretreatment studies, 10 (3 mg/kg), KML29 (3 mg/kg) or URB597 (3 mg/kg) dissolved in 300 μL saline containing 5% ethanol, 5% DMSO and 5% Tween^® 80 was injected at 30 min via the tail vein catheter before the injection of 16. For displacement (“chase”) studies, KML29 (3 mg/kg) was injected at 15 min via the tail vein catheter after the injection of 16. As we previously reported,^{46 (link), 90 (link), 91 (link)} the PET dynamic images were reconstructed using ASIPro VW software (Analysis Tools and System Setup/Diagnostics Tool, Siemens Medical Solutions). Volumes of interest, including the whole brain, cerebral cortex, cerebellum, striatum, thalamus and pons were placed referencing the MRI template software. The radioactivity was decay-corrected and expressed as the standardized uptake value. SUV = (radioactivity per mL tissue/injected radioactivity) x body weight.

Cheng R., Mori W., Ma L., Alhouayek M., Hatori A., Zhang Y., Ogasawara D., Yuan G., Chen Z., Zhang X., Shi H., Yamasaki T., Xie L., Kumata K., Fujinaga M., Nagai Y., Minamimoto T., Svensson M., Wang L., Du Y., Ondrechen M.J., Vasdev N., Cravatt B.F., Fowler C., Zhang M.R, & Liang S.H. (2018). In vitro and In vivo evaluation of 11C-labeled azetidine-carboxylates for imaging monoacylglycerol lipase by PET imaging studies. Journal of medicinal chemistry, 61(6), 2278-2291.

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Imaging Brain Receptor Dynamics in Rats

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PET scans were conducted by an Inveon PET scanner (Siemens Medical Solutions, Knoxville, TN, USA). Sprague-Dawley rats were kept under anesthesia with 1-2% (v/v) isoflurane during the scan. The radiotracer (1.08-1.35 mCi / 200 µL) was injected via a preinstalled catheter via tail vein. A dynamic scan in 3D list mode was acquired for 90 min. For pretreatment studies, URB597 (3 mg/kg), SAR127303 (1 mg/kg), JZL184 (3 mg/kg) or KML29 (3 mg/kg) dissolved in 300 µL saline containing 10% ethanol and 5% Tween^® 80 was injected at 30 min via the tail vein catheter before the injection of [¹¹C]SAR127303 ([¹¹C]5a) or [¹¹C]TZPU ([¹¹C]5f). As we previously reported,43 the PET dynamic images were reconstructed using ASIPro VW software (Analysis Tools and System Setup/Diagnostics Tool, Siemens Medical Solutions). Volumes of interest, including the whole brain, cerebral cortex, cerebellum, striatum, thalamus and pons were placed using ASIPro software. The radioactivity was decay-corrected and expressed as the standardized uptake value. SUV = (radioactivity per mL tissue / injected radioactivity) x body weight.

Wang L., Mori W., Cheng R., Yui J., Hatori A., Ma L., Zhang Y., Rotstein B.H., Fujinaga M., Shimoda Y., Yamasaki T., Xie L., Nagai Y., Minamimoto T., Higuchi M., Vasdev N., Zhang M.R, & Liang S.H. (2016). Synthesis and Preclinical Evaluation of Sulfonamido-based [11C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics, 6(8), 1145-1159.

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PET Imaging of Radiotracer Uptake in Rats

Cited 3 times

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The general procedure for PET studies was described previously^{39 (link), 41 (link)} with minor modification in this work. Briefly, PET scans were carried out by an Inveon PET scanner (Siemens Medical Solutions, Knoxville, TN, USA). Sprague-Dawley rats were kept under anesthesia using 1–2% (v/v) isoflurane during the scan. The radiotracer (ca. 1 mCi / 150 μL) was injected into the tail vein via a preinstalled catheter. A dynamic scan in 3D list mode was acquired for 90 min. For pretreatment studies, a solution of KML29 (3 mg/kg) in 300 μL saline containing 10% ethanol and 5% Tween^® 80 was injected via the pre-embedded tail vein catheter at 30 min prior to tracer injection. As we previously reported,^{39 (link), 77 (link), 78 (link)} the PET dynamic images were reconstructed using ASIPro VW software (Analysis Tools and System Setup/Diagnostics Tool, Siemens Medical Solutions). Volumes of interest, including the whole brain, hippocampus, cerebral cortex, cerebellum, striatum, thalamus, and pons were placed using ASIPro software. The radioactivity was decay-corrected and expressed as the standardized uptake value. SUV = (radioactivity per mL tissue / injected radioactivity) × body weight.

Chen Z., Mori W., Deng X., Cheng R., Ogasawara D., Zhang G., Schafroth M.A., Dahl K., Fu H., Hatori A., Shao T., Zhang Y., Yamasaki T., Zhang X., Rong J., Yu Q., Hu K., Fujinaga M., Xie L., Kumata K., Gou Y., Chen J., Gu S., Bao L., Wang L., Lee Collier T., Vasdev N., Shao Y., Ma J.A., Cravatt B.F., Fowler C., Josephson L., Zhang M.R, & Liang S.H. (2019). Design, synthesis and evaluation of reversible and irreversible monoacylglycerol lipase positron emission tomography (PET) tracers using a ‘tail switching’ strategy on a piperazinyl azetidine skeleton. Journal of medicinal chemistry, 62(7), 3336-3353.

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