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Acetonitrile of high performance liquid chromatography grade

Manufactured by Thermo Fisher Scientific
Sourced in United States

Acetonitrile of high performance liquid chromatography (HPLC) grade is a solvent used in HPLC applications. It is a colorless, volatile, and flammable liquid with a characteristic odor. Acetonitrile HPLC grade is used as a mobile phase component in HPLC analyses to facilitate the separation, identification, and quantification of various compounds.

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2 protocols using acetonitrile of high performance liquid chromatography grade

1

Ritonavir Polymorphic Form II Characterization

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Ritonavir (Polymorphic Form II) was obtained from Anhui Biochem United Pharmaceutical Co., Ltd. (Hefei, China) that was used without further purification. Ritonavir Reference Standard (99.3%) was purchased from The United States Pharmacopeial Convention (North Bethesda, MD, USA). PVPVA (Kollidon® VA 64) was supplied by BASF Corporation (Ludwigshafen, Germany). Sorbitan monolaurate (Span 20-LQ-(AP)) was obtained from Croda Inc. (East Yorkshire, UK). The ultrapure water was purified by the Milli-Q® Advantage A10® water purification system (Millipore, MA, USA). Acetonitrile of high performance liquid chromatography (HPLC) grade was obtained by Thermo Fisher Scientific (Newington, NH, USA). Methanol was provided by Adamas Pharmaceuticals, Inc. (Shanghai, China). Potassium dihydrogen phosphate and phosphoric acid were supplied from Tianjin Zhiyuan Chemical Reagent Co., Ltd. (Tianjin, China).
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2

Quantification of Linezolid and Chloramphenicol

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Linezolid standard (purity of 99.58% in powder form) was purchased from MedChem Express (Monmouth Junction, NJ, USA). Chloramphenicol standard (purity of 99.8% in powder form) was obtained from the National Institutes for Food and Drug Control (Beijing, People’s Republic of China). Linezolid for injection (Zyvox®, Fresenius Kabi Norge AS, Halden, Norway) was purchased from Fresenius Kabi Norge AS (Oslo, Norway). Acetonitrile of high-performance liquid chromatography (HPLC) grade was obtained from Thermo Fisher Scientific (Waltham, MA, USA). Milli-Q™ water (EMD Millipore, Billerica, MA, USA) was used for all samples.
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