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Signa advantage

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The Signa Advantage is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to provide high-quality imaging capabilities for medical professionals. The core function of the Signa Advantage is to generate detailed images of the body's internal structures, enabling healthcare providers to diagnose and monitor various medical conditions.

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Lab products found in correlation

Signa hdx 3t, by GE Healthcare (1 mentions) Signa hdx, by GE Healthcare (1 mentions) Magnetom vision, by Siemens (1 mentions)

Close spelling variants of this product

Signa Advantage system (2 citations) 1.5 T Signa Advantage system (2 citations) Signa Advantage Horizon (2 citations)

5 protocols using signa advantage

1

3T MRI and Diffusion Imaging Protocol

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MRI images were acquired on a 3.0T Signa Advantage system (GE Healthcare, Waukesha, WI, USA). Anatomical T1-3D images were acquired with the following parameters: echo time (TE) = 2.8 ms, repetition time (TR) = 7.1 ms, field of view (FOV) 256×256 mm2, matrix size=256×256, slice thickness=1 mm (voxel size 1×1×1 mm3), number of slices=178, with an acquisition time of 5 minutes. Diffusion images were acquired using a single-shot EPI (echo planar imaging) sequence. Scan parameters were as follows: TR = 14000 ms, TE = 82 ms, flip angle 90 degrees, slice thickness=3 mm, Number of Excitation for signal averaging (NEX) = 1, FOV (field of view) = 240×240 mm2, voxel dimensions = 0.95×0.95×3 mm, acquisition matrix=256×256, b value = 1000 s/mm2, and 25 collinear directions with 5 non-weighted images. DTI scan time was approximately 11 minutes.
Chhetry B.T., Hezghia A., Miller J.M., Lee S., Rubin-Falcone H., Cooper T.B., Oquendo M.A., Mann J.J, & Sublette M.E. (2016). Omega-3 Polyunsaturated Fatty Acid Supplementation and White Matter Changes in Major Depression. Journal of psychiatric research, 75, 65-74.
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2

MRI Imaging for PET Co-registration

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As previously described (Parsey et al., 2000 (link)), MRI images were acquired on either a 1.5T Signa Advantage or a 3T Signa HDx system (General Electric Medical Systems, Milwaukee, WI) for co-registration with PET images and extraction of ROIs.
Gopaldas M., Zanderigo F., Zhan S., Ogden R.T., Miller J.M., Rubin-Falcone H., Cooper T.B., Oquendo M.A., Sullivan G., Mann J.J, & Sublette M.E. (2019). Brain Serotonin Transporter Binding, Plasma Arachidonic Acid and Depression Severity: a Positron Emission Tomography Study of Major Depression. Journal of affective disorders, 257, 495-503.
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3

T1-weighted MRI acquisition for PET co-registration

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Acquisition of T1-weighted MRI images for co-registration of PET images and identification of regions of interest (ROIs) was performed as previously described using a 1.5 T Signa Advantage or a 3 T Signa HDx system (General Electric Medical Systems, Milwaukee, WI) (Parsey et al., 2000 (link)).
Miller J.M., Everett B.A., Oquendo M.A., Ogden R.T., Mann J.J, & Parsey R.V. (2015). Positron Emission Tomography Quantification of Serotonin Transporter Binding in Medication-Free Bipolar Disorder. Synapse (New York, N.Y.), 70(1), 24-32.
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4

Multimodal Imaging in Medical Research

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All imaging was performed at the radiology department in our institution. Computed tomography (CT) was performed in 8 patients, magnetic resonance imaging (MRI) in 2 patients, and 18fluorine-labeled glucose positron emission tomography (PET) scanning in 2 of the 9 patients. Three patients underwent imaging with multiple modalities. CT scans were obtained in the axial plane by using a helical CT scanner with 2.5-mm-thick sections after the intravenous administration of iodinated contrast material. MRI was performed with a 1.5-T magnet (Signa Advantage; GE Healthcare, Milwaukee, WI, USA).
Lee J.Y., Chung H., Cho H., Jang J.E., Kim Y., Kim S.J., Kim J.S., Hyun S.Y., Min Y.H, & Cheong J.W. (2017). Clinical characteristics and treatment outcomes of isolated myeloid sarcoma without bone marrow involvement: a single-institution experience. Blood research, 52(3), 184-192.
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5

Shoulder MRI Imaging Protocol

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MRI was performed with a 1.5 T MR system (Signa Advantage; General Electric Medical Systems, Milwaukee, WI or Magnetom Vision, Siemens Medical System, Erlangen, Germany) with appropriate surface coils for shoulder imaging. Patients were positioned with the humeral in a neutral position. MRI protocols included the following: oblique coronal fast T2-weigthed images with fat saturation (TR/TE: 3000 54 ms) and T1-weighted images (TR/TE: 500/minimalms), oblique sagittal fast T2-weighted images (TR/TE: 3000/90 ms), axial gradient echo images (TR/TE: 450/20, 20 flip angle), and fast T2-weighted images with fat saturation (TR/TE: 3000/50 ms). All the sequences used a matrix of 256 × 192, two excitations, a 14 cm field of view (FOV), a 4 mm section thickness and 0.4 mm intersection gap. For the fast T2-weighted images, the echo trains were 8.
Cheng X., Zhang Z., Xuanyan G., Li T., Li J., Yin L, & Lu M. (2017). Adhesive Capsulitis of the Shoulder: Evaluation With US-Arthrography Using a Sonographic Contrast Agent. Scientific Reports, 7, 5551.
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