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Skyra 3t mri system

Manufactured by Siemens
Sourced in Germany

The Skyra 3T MRI system is a magnetic resonance imaging (MRI) device produced by Siemens. It operates at a field strength of 3 Tesla, providing high-quality imaging capabilities. The core function of the Skyra 3T MRI system is to generate detailed images of the human body for diagnostic and research purposes.

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8 protocols using skyra 3t mri system

1

Neonatal Brain MRI Acquisition Protocol

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Newborns were scanned during natural and unsedated sleep. A Siemens Skyra 3 T MRI system equipped with a 20-channel head coil at the Brain Imaging Center at the University of Colorado Anschutz Medical Campus was used. Prior to scanning, newborns were fed, swaddled, and placed into the scanner with their heads secured in a vacuum-fixation device to limit scan noise due to motion. Newborns wore earplugs and headphones to prevent wakefulness from the acoustic noise of the scan. Newborns were monitored by a research staff member who was in the scanner for the entirety of the scan and caregivers remained in the scan room if they chose to do so.
T1-weighted (T1w) images were obtained using a three-dimensional magnetization-prepared rapid gradient echo sequence (repetition time = 1900 ms; echo time = 3.07 ms; inversion time = 900 ms; flip angle 9°; 4 min 26 s) and T2-weighted (T2w) images were obtained with a 3D fast turbo spin echo sequence (repetition time 3200 ms; echo time = 408 ms; flip angle var; 4 min 43 s). The spatial resolution was a 0.82 × 0.82 × 0.8 mm voxel for T1w and 0.86 mm × 0.86 mm × 0.8 mm voxel for T2w.
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2

Infant Brain Imaging During Natural Sleep

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Infants were scanned during natural sleep. A Siemens Skyra 3T MRI system equipped with a 20-channel head coil at the Brain Imaging Center at the University of Colorado Anschutz Medical Campus was used. Before scanning, infants were fed, swaddled, and placed into the scanner with their head secured within a vacuum-fixation device to limit motion. Infants wore earplugs and headphones to limit the acoustic noise of the scan. Infants were monitored by a research staff member who was in the scanner with the infant for the duration of the scan.
T1-weighted (T1w) images were obtained using a three-dimensional magnetization-prepared rapid gradient echo sequence (repetition time = 1900 ms; echo time = 3.07 ms; inversion time = 900 ms; flip angle 9°; 4 min 26 s) and T2-weighted (T2w) images were obtained with a 3D fast turbo spin echo sequence (repetition time 3200 ms; echo time = 408 ms; flip angle var; 4 min 43 s). The spatial resolution was a 0.82 × 0.82 × 0.8 mm voxel for T1w and 0.86 mm × 0.86 mm × 0.8 mm voxel for T2w.
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3

Diffusion Tensor Imaging of Infant Brain During Sleep

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Infants were scanned unsedated during natural sleep. Noise from the
scanner was reduced by the use of malleable ear plugs and neonatal ear covers.
Headphones played white noise during image acquisition. A Siemens Skyra 3T MRI
system equipped with a 20-channel head coil at the Brain Imaging Center at the
University of Colorado Anschutz Medical Campus was used.
Diffusion tensor images were obtained using a simultaneous multislice
sequence (SMS; TR = 6100 ms, TE = 60, FOV = 220, matrix size = 128 × 128;
50 axial slices with 2.0 mm thickness; PE direction = AP). Diffusion MRI data
were acquired with three diffusion weightings (b-values) (b = 300, 800, 2000
s/mm2), with 10, 30, and 64 unique gradient directions per
respective shell (104 gradient directions total). In addition, 18 interspersed b
= 0 s/mm2 images were acquired as a baseline. The total acquisition
time was 7 min (multiband acceleration 3, echo time (TE)/TR 92/3,600 ms).
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4

High-Resolution MRI and Diffusion Imaging Protocol

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MR scanning was conducted using a Siemens Skyra 3 T MRI system (Erlangen, Germany) with a 32-channel receive only head coil. High resolution T1-weighted 3D MPRAGE images were acquired for each participant using the following parameters: TR = 1900 ms, TI = 900 ms, TE = 2.49 ms, flip angle = 9°, voxel size = 0.9 mm3, acquisition matrix 256 × 256, FoV = 240 mm, 192 contiguous slices with an acquisition time of 4:26 min. High angular resolution diffusion imaging (HARDI) was conducted using a single shot EPI sequence with the following parameters: TR = 8500 ms, TE = 110 ms, flip angle = 90°, voxel size = 2.5 mm3, acquisition matrix 96 × 96, FoV = 240 mm, 60 contiguous slices. A total of 64 non-collinear diffusion weighted directions with b = 3000 s/mm2 were captured, and 8 non-weighted images (b = 0 s/mm2) interleaved between the weighted images. Acquisition time was 10:32 min. The higher b-value adopted here relative to previous studies of white matter organization in DCD was used to improve the resolution of distinct fibre orientations for tractography (Caan, 2016 ).
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5

Multimodal MRI Protocol for Brain Imaging

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All participants were scanned with Siemens Magnetom Skyra 3T MRI system using a 32Ch head coil. The MRI protocol was as follows: 3D T1-weighted MRI was collected with MPRAGE: coronal, TR 2200 ms, TE 2.42 ms, TI 900 ms, flip angle 9°, resolution 0.34 x 0.34 x 1.60 mm 3 (after 2-fold interpolation in-plane), matrix size 540 x 640 x 144 (after 2-fold interpolation in-plane), GRAPPA factor 2, time 5:25. Quantitative T2 images were acquired with a multi-contrast spin-echo sequence: coronal, TR 4500, TE 12 ms, number of echoes 10, echo spacing 12 ms, resolution 0.34 x 0.34 x 1.7 mm 3 (after 2-fold interpolation in-plane, and inclusive of 15% slice gap), matrix size 540 x 640, 34 slices, GRAPPA factor 2, time 11:07.
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6

Functional Neuroimaging of the Brain

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All data were acquired at the University of California Davis Imaging Research Center on a 3T Skyra MRI System (Siemens Healthcare, Erlangen, Germany) using a 64 channel phased-array head coil. Functional images were obtained using T2* fast field echo, echo planar functional images (EPIs) sensitive to BOLD contrast (SBF experiment: TR = 2 s, TE = 25 ms, 32 axial slices, 3.0 mm2, matrix size = 80 × 80, 3.5 mm thickness, interleaved slice acquisition, 0.5 mm gap, FOV = 240 × 240, flip angle = 71°; retinotopic mapping: same, except 32 axial slices, TR = 2.5 s). High-resolution structural scans were collected to support reconstruction of the cortical hemisphere surfaces using FreeSurfer from T1 (MPRAGE, TR=2230 ms, TE=4.02 ms, FA=7°, 640x640 matrix, res =0.375×0.375×0.8 mm) and T2 (TR=3s, TE=304 ms, FA=7°, 640×640 matrix, res =0.375×0.375×0.8 mm) images.
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7

Hippocampal and EVC Functional Imaging

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All images were acquired on a Siemens 3 T Skyra MRI system in the Lewis Center for Neuroimaging at the University of Oregon. Functional data were acquired with a T2*-weighted echo-planar imaging sequence with partial-brain coverage that prioritized full coverage of the hippocampus and EVC (repetition time = 2000 ms, echo time = 36 ms, flip angle = 90°, 72 slices, 1.7 × 1.7 × 1.7 mm voxels). A total of eight functional scans were acquired. Each functional scan comprised 177 volumes and included 10 s of lead-in time and 10 s of lead-out time at the beginning and end of each scan, respectively. The eight functional scans corresponded to six scans of the scene exposure phase (scans 1 and 3–7) and two scans of the object exposure phase (scans 2 and 8). Anatomical scans included a whole-brain high-resolution T1-weighted magnetization prepared rapid acquisition gradient-echo anatomical volume (1 × 1 × 1 mm voxels) and a high-resolution (coronal direction) T2-weighted scan (0.43 × 0.43 × 2 mm voxels) to facilitate segmentation of hippocampal subfields.
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8

Functional MRI of Cortical Mapping

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All data were acquired at the University of California Davis Imaging Research Center on a 3T Skyra MRI System (Siemens Healthcare, Erlangen, Germany) using a 64 channel phased-array head coil. Functional images were obtained using T2* fast field echo, echo planar functional images (EPIs) sensitive to BOLD contrast (WM task: TR = 2 s, TE = 25 ms, 32 axial slices, 3.0 mm2, matrix size = 80 × 80, 3.5 mm thickness, interleaved slice acquisition, 0.5 mm gap, FOV = 240 × 240, flip angle = 71°; retinotopic mapping: same, except 32 axial slices, TR = 2.5 s). High-resolution structural scans (MPRAGE: 208 sagittal slices, 0.9 mm2 in-plane voxel resolution, matrix size = 256 × 256, slice-thickness = 0.95 mm, FOV = 243 × 243 × 187 mm, TE = 4.33 ms, TR = 10 ms, flip angle = 7°) were collected to support reconstruction of the cortical hemisphere surfaces using FreeSurfer (http://surfer.nmr.mgh.harvard.eduDale, Fischl, & Sereno, 1999 (link); Fischl, Sereno, & Dale, 1999 (link)).
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