Patients who underwent standard partial brain RT for low-grade or benign cranial tumors were enrolled in an IRB approved study. Inclusion criteria consisted of full completion of the study, minimal to no missing data, no major imaging artifact, and no tumor progression or severe complication (e.g., seizure, hydrocephalus or hemorrhage). This yielded 33 analyzable patients in total from study cohort.
MRI scans were performed at six time points: 1-2 weeks pre-RT, 3 and 6 weeks during RT, and 1, 6 and 18 months after RT. Nine, fifteen and nine patients had all their scans on GE 1.5T, Philips 3T and Siemens 3T scanners, respectively. All T1-weighted images had a resolution of 1×1×1mm3. DTI were acquired with (GE/Philips/Siemens): TR=9300/7073/4600ms with minimized TE, resolution=1.25×1.25×4mm3/1.75×1.75×2mm3/1.72×1.72×3.9mm3, b=1000/800/1000s/mm2, and the number of unique diffusion-weighting directions=9/15/20, respectively.
MRI scans were performed at six time points: 1-2 weeks pre-RT, 3 and 6 weeks during RT, and 1, 6 and 18 months after RT. Nine, fifteen and nine patients had all their scans on GE 1.5T, Philips 3T and Siemens 3T scanners, respectively. All T1-weighted images had a resolution of 1×1×1mm3. DTI were acquired with (GE/Philips/Siemens): TR=9300/7073/4600ms with minimized TE, resolution=1.25×1.25×4mm3/1.75×1.75×2mm3/1.72×1.72×3.9mm3, b=1000/800/1000s/mm2, and the number of unique diffusion-weighting directions=9/15/20, respectively.