Nicotine bitartrate, varenicline tartrate, and Bupropion hydrochloride were dissolved in 0.9% sterile saline. Intravenous nicotine dose (0.03 mg/kg/inf; MP Biomedicals; Solon, OH, USA) and nicotine subcutaneous injection dose (0.4 mg/kg) were chosen based on previous research (Charntikov et al., 2014 (link); Liu et al., 2008 (link)). Bupropion hydrochloride and varenicline tartrate were obtained from Toronto Research Chemicals (Toronto, ON, Canada). Doses and administration protocols were adopted from previous research (Bruijnzeel and Markou, 2003 (link); George et al., 2011 (link); Liu et al., 2008 (link); Shoaib et al., 2003 (link); Wouda et al., 2011 (link)). Nicotine doses are reported as base, whereas bupropion and varenicline doses are reported as salt.
Varenicline tartrate
Manufactured by LGC
Sourced in Canada
Varenicline tartrate is a chemical compound used as a laboratory reagent. It is a salt form of varenicline, which is a medication used to help people quit smoking. Varenicline tartrate can be utilized in various research and analytical applications.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using varenicline tartrate
1
Nicotine, Bupropion, and Varenicline Pharmacology
2
Oxycodone and Varenicline Synthesis
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Varenicline tartrate was purchased from Toronto Research Chemicals Inc. (Toronto, Canada). Oxycodone was kindly provided by Takeda Pharmaceutical Company Ltd. (Osaka, Japan). All other chemicals and reagents were commercial products of reagent grade, purchased from Wako Pure Chemical Industries (Osaka, Japan) or Sigma-Aldrich Company (St. Louis, MO). The details of the buffers are presented in the Supplementary Information.
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