Nlrp3 ko b6.129s6 nlrp3 jtm1bhk

The BALB/c mice used were obtained from the Comisión Nacional de Energía Atómica (Buenos Aires, Argentina). Male TNFα-RKO (B6.129-Tnfrsf1a^tm1Mak), IL6KO (B6.129S2-Il6/^Jtm1Copf), and NLRP3 KO (B6.129S6-Nlrp3/J^tm1Bhk) mice were purchased from the Jackson Laboratory. Male C57BL/6J mice were from Universidad Nacional de La Plata (Argentina). All mice were inbred and housed according to institutional guidelines (28 ).

Six- to eight-week-old inbred female C57BL/6 mice indicated as wild type (WT) along the manuscript, were obtained from the Faculty of Veterinary Sciences, National University of Litoral (UNL, Argentina). CASP1/11 KO (B6N.129S2-Casp1^tm1Flv/J) and NLRP3 KO (B6.129S6-Nlrp3/^Jtm1Bhk) mice, on a C57BL/6 background, were purchased from Jackson Laboratory (Bar Harbor, ME, USA). The BALB/c mice used were obtained from the Comisión Nacional de Energía Atómica (Buenos Aires, Argentina).
All animal experiments were approved by and conducted in accordance with guidelines of the committee for Animal Care and Use of the Faculty of Chemical Sciences, National University of Córdoba (Approval Number HCD 1637) in strict accordance with the recommendation of the Guide to the Care and Use of Experimental Animals published by the Canadian Council on Animal Care (OLAW Assurance number A5802-01).