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Ultrapro mesh

Manufactured by Johnson & Johnson
Sourced in United States

Ultrapro® mesh is a surgical implant material used in hernia repair procedures. It is composed of polypropylene and polyglecaprone 25. The mesh provides reinforcement and support for the repair of weakened or damaged tissue.

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2 protocols using ultrapro mesh

1

Transabdominal Preperitoneal Mesh Repair

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The abdomen will be accessed and the pneumoperitoneum will be achieved with standard laparoscopic techniques. The preperitoneal space will be exposed transabdominally with a sharp incision, followed by bluntly stripping the peritoneum that overlies the inguinal anatomy. An Ultrapro® mesh (Ethicon Inc., Johnson & Johnson, Somerville, NJ, USA) will be deployed and fixed in place with either staples or glue, and then the peritoneum will be returned to its anatomical position.
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2

Comparative Evaluation of Mesh Implants

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Test devices included uncoated and ECM coated heavy-weight BARD™ polypropylene mesh (C.R. BARD, city, state), uncoated and ECM coated light-weight BARD™ Soft poly-propylene mesh (C.R. BARD), and uncoated light-weight Ultra-Pro™ mesh (Ethicon.). These devices were implanted in a previously described [24 (link)–26 (link)] rat partial thickness bilateral abdominal defect overlay model. The two time points investigated were 14 and 180 days. Histomorphologic scoring of the tissue remodeling response as well as macrophage phenotype characterization were performed at 14 days. Histomorphologic assessment, collagen deposition characterization, and biaxial testing were performed at 180 days post implantation. A total of 80 mesh devices were implanted, and 40 animals were used over the course of the study (i.e., bilateral implants per animal); 20 mesh devices were implanted for the 14 day time point (n-value = 4 for each device), 60 mesh devices were implanted for the 180 day time point (n-value = 12 for each device, 8 for biaxial testing and 4 for histology).
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