Cp100356

Manufactured by Bio-Techne

Sourced in United Kingdom

The CP100356 is a piece of lab equipment manufactured by Bio-Techne. It is designed to perform a specific function within the laboratory setting. No further details about its intended use or capabilities can be provided in an unbiased and factual manner.

Automatically generated - may contain errors

Lab products found in correlation

Gentamicin, by Thermo Fisher Scientific (3 mentions) Hepes, by MP Biomedicals (3 mentions) Ketoconazole, by Merck Group (2 mentions) Quinidine, by Merck Group (2 mentions) Ketoconazole, by MP Biomedicals (2 mentions) Amphotericin b fungizone solution, by Thermo Fisher Scientific (2 mentions) Cyclosporine a, by MP Biomedicals (2 mentions) Psc833, by MP Biomedicals (2 mentions) Cp100356, by MP Biomedicals (2 mentions) Verapamil hydrochloride, by Merck Group (2 mentions) Verapamil, by MP Biomedicals (2 mentions) Psc833, by Bio-Techne (2 mentions) Rhodamine 123, by Merck Group (1 mentions) Quinidine, by MP Biomedicals (1 mentions) Cyclosporine a, by Merck Group (1 mentions) Agarose, by Merck Group (1 mentions) 3 hydroxyquinidine, by LGC (1 mentions) Fungizone amphotericin b, by Thermo Fisher Scientific (1 mentions)

3 protocols using cp100356

Multimodal Assay for Drug Efflux

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Rhodamine 123, verapamil hydrochloride, cyclosporine A, ketoconazole, quinidine and low gelling temperature agarose (type VII-A) were purchased from Sigma-Aldrich (USA). PSC833 and CP100356 were from Tocris Bioscience (UK). Gentamicin, Williams Medium E (WME) with glutamax-I, and amphotericin B (fungizone) solution were obtained from Invitrogen (UK). HEPES was obtained from MP Biomedicals (Germany).
The stock solutions were prepared in ethanol (R123), methanol (quinidine) or DMSO (verapamil, cyclosporine A, ketoconazole, PSC833 and CP100356).

Li M., de Graaf I.A., de Jager M.H, & Groothuis G.M. (2015). Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo. Toxicology in vitro : an international journal published in association with BIBRA, 29(5).

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Compound Screening for Cellular Assays

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Quinidine, verapamil hydrochloride, ketoconazole and agarose (low gelling temperature, type VII-A) were from Sigma-Aldrich (USA). PSC833 and CP100356 were obtained from Tocris Bioscience (UK). Amphotericin B (fungizone)-solution, gentamicin, and William's medium E with glutamax-I (WME) were purchased from Invitrogen (UK). HEPES was from MP Biomedicals (Germany). Antipyrine was purchased from O. P. G. Pharma (the Netherlands). 3-Hydroxy-Quinidine was purchased from Toronto Research Chemicals Inc. (Canada).

Li M., de Graaf I.A., van de Steeg E., de Jager M.H, & Groothuis G.M. (2017). The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo. Toxicology in vitro : an international journal published in association with BIBRA, 40.

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Cell Membrane Transport Assay

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Rhodamine 123 (R123), ketoconazole, cyclosporine A, quinidine, verapamil hydrochloride, and agarose (low gelling temperature, type VII-A) were from Sigma-Aldrich
amine)and CP100356 were purchased from Tocris Bioscience (Bristol, UK). Williams Medium E with glutamax-I, gentamicin, and amphotericin B (fungizone) solution were from Invitrogen (Paisley, UK). HEPES was obtained from MP Biomedicals (Heidelberg, Germany).
The stock solutions were prepared in ethanol (R123), methanol (quinidine) or DMSO (verapamil, cyclosporine A, ketoconazole, PSC 833 and CP100356).

Li M., de Graaf I.A., de Jager M.H, & Groothuis G.M. (2017). P-gp activity and inhibition in the different regions of human intestine ex vivo. Biopharmaceutics & drug disposition, 38(2).

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