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Lal shrna 1 and 2

Manufactured by Merck Group

LAL shRNA #1 and #2 are laboratory reagents used for gene silencing experiments. They contain short hairpin RNA (shRNA) sequences targeting the Lamin A/C (LAL) gene. These shRNA products are designed to reduce the expression of the LAL gene in cell-based models, allowing researchers to study the effects of LAL knockdown. No further details on intended use or applications are provided.

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2 protocols using lal shrna 1 and 2

1

Lentiviral shRNA Knockdown Protocol

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Human scrambled shRNA, FIP200 shRNA, and Tsc1 shRNA encoded in pGIPZ lentiviral vector were purchased from Open Biosystems (Lafayette, CO). Mouse scrambled shRNA, LAL shRNA #1 and #2 were purchased from Sigma. Package vectors of pSPAX2 and pMD2.G were mixed with shRNA vectors and transfected in HK293 cells for virus production essentially as described before37 (link).
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2

Lentiviral shRNA Knockdown Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Human scrambled shRNA, FIP200 shRNA, and Tsc1 shRNA encoded in pGIPZ lentiviral vector were purchased from Open Biosystems (Lafayette, CO). Mouse scrambled shRNA, LAL shRNA #1 and #2 were purchased from Sigma. Package vectors of pSPAX2 and pMD2.G were mixed with shRNA vectors and transfected in HK293 cells for virus production essentially as described before37 (link).
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