R r studio software

The collected data were stored in a Microsoft Excel spreadsheet (Microsoft Inc., Redmond, WA, USA). Statistical analyses were conducted on an intention-to-treat basis, using SPSS software (SPSS, version 22 for Windows; SPSS Inc., Chicago, IL, USA) and R/R Studio software. The analyses were conducted using the Modified Intention-To-Treat population, which consisted of all the randomized participants who underwent at least one angioembolization [26 (link),27 (link)]. The Kolmogorov–Smirnov and Shapiro–Wilk tests were employed to validate the normality assumption of the data. Categorical data are shown as a frequency (% value) [28 (link)]. Continuous data are reported as previously described [29 (link),30 (link)]. The unpaired Student’s t-test [31 (link)], the chi-squared/Fisher’s exact tests, and the Wilcoxon rank-sum test [32 (link),33 (link)] were performed as appropriate. For the tests stated above, a p-value of 0.05 was considered statistically significant.

The data were recorded and organized in a Microsoft Excel spreadsheet (Microsoft Inc, Redmond, WA, USA), while statistical analyses were conducted based on the intention-to-treat principle using SPSS software (version 22 for Windows; SPSS Inc, Chicago, IL, USA) and R/R Studio software. The Modified Intention-To-Treat population, consisting of all randomized patients who underwent at least one embolization procedure, was utilized for the subsequent analyses [37 (link),38 (link)]. Kolmogorov–Smirnov and Shapiro–Wilk tests were performed to verify the normality assumption of data. Categorical data are presented as frequencies (% value) [39 (link)]. Continuous data with a normal distribution are expressed as mean ± standard deviation, whereas continuous data that do not follow a normal distribution are presented as median (first to third quartile) [40 (link),41 (link)]. Statistical differences in continuous data with a normal distribution were assessed using the unpaired Student t-test, while categorical data and continuous data without a normal distribution were evaluated using the Chi-squared/Fisher’s exact tests and the Mann–Whitney test, respectively [42 (link),43 (link),44 (link)]. A p-value of less than 0.05 was considered statistically significant for all the aforementioned tests.

All randomized patients who underwent at least one embolization treatment were included in the analysis as the Modified Intention-To-Treat population [44 (link),45 (link)]. The data’s assumed normality was checked using the Kolmogorov–Smirnov and Shapiro–Wilk tests. Frequency (% value) is the presentation format for categorical data [46 (link)]. Data with a continuous normal distribution are shown as mean ± standard deviation. Data that are continuous but not normally distributed are shown as the median (first to third quartile) [47 (link),48 (link)]. Continuous normally distributed data were evaluated using an unpaired Student’s t-test, whilst categorical and continuous not normally distributed data were evaluated using the Chi-squared/Fisher’s exact tests and the Mann–Whitney test, respectively. [49 (link),50 (link),51 (link)]. The aforementioned tests were deemed statistically significant at a p-value of 0.05. The data were maintained in an Excel spreadsheet (Microsoft Inc, Redmond, Wash) and the statistical analyses were performed on an intention-to-treat basis, using SPSS software (SPSS, v. 22 for Windows; SPSS Inc., Chicago IL, USA) and R/R Studio software.