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Nigericin sodium salt

Manufactured by Selleck Chemicals
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Nigericin sodium salt is a chemical compound that functions as an ionophore, facilitating the transport of monovalent cations, such as potassium and sodium, across biological membranes. It is commonly used in cell biology research as a tool to study ion homeostasis and membrane potential.

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Lab products found in correlation

Cycloheximide (chx), by Selleck Chemicals (2 mentions) Bortezomib, by MedChemExpress (2 mentions) Hydrocortisone, by MedChemExpress (2 mentions) Hydroxychloroquine, by MedChemExpress (2 mentions) Leupeptin hemisulfate, by MedChemExpress (2 mentions) Dextran sulfate sodium salt, by MedChemExpress (2 mentions) Curcumin, by MedChemExpress (2 mentions) Lipopolysaccharide lps from escherichia coli o111 b4, by Merck Group (2 mentions) Nh4cl, by Sangon (2 mentions) Bafilomycin a1, by MedChemExpress (2 mentions) β mercaptoethanol, by Thermo Fisher Scientific (2 mentions) 3 methyladenine, by MedChemExpress (2 mentions) D galactosamine d galactosamine, by Merck Group (2 mentions) Disuccinimidyl suberate dss, by MedChemExpress (2 mentions) Phorbol 12 myristate 13 acetate, by Selleck Chemicals (2 mentions) Np 40 lysis buffer, by Apexbio (2 mentions) Z vad fmk, by Selleck Chemicals (2 mentions) Rapamycin, by MedChemExpress (2 mentions) Mg132, by MedChemExpress (2 mentions) Lipopolysaccharides (lps), by Merck Group (1 mentions)

3 protocols using nigericin sodium salt

1

Comprehensive Protocol for Cell Stress Assays

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JNUTS013 (≥98% purity) was synthesized in the Tang laboratory. Lipopolysaccharide (LPS, from Escherichia coli O111:B4) was purchased from Sigma-Aldrich (Cat#L2630, Steinheim, Germany). Dimethyl sulfoxide (DMSO) was purchased from Aladdin Bio-Chem Technology (Cat#67–68-5, Shanghai, China). d-galactosamine (D-galactosamine) was purchased from Sigma-Aldrich (Cat#G1639, Steinheim, Germany). Hydrocortisone (Cat#HY-N0583), curcumin (Cat#HY-N0005), rapamycin (Cat#HY-10219), MG132 (Cat#HY-13259), bortezomib (Cat#HY-10227), hydroxychloroquine (Cat#HY-W031727), leupeptin hemisulfate (Cat#HY-18234A), bafilomycin A1 (Cat#HY-100558), 3-methyladenine (Cat#HY-19312), dextran sulfate sodium salt (DSSS, Cat#HY-116282B) and disuccinimidyl suberate (DSS) (Cat#HY-W019543) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). Phorbol 12-myristate 13-acetate (PMA, Cat#S7791), nigericin sodium salt (Cat#S6653), cycloheximide (Cat#S7418) and Z-VAD-FMK (Cat#S7023) were purchased from Selleckchem (Houston, TX, USA). NP-40 lysis buffer (Cat#K1127) was purchased from Apexbio (Houston, TX, USA). NH4Cl (Cat#A100621) was purchased from Sangon Biotech (Shanghai, China). β-Mercaptoethanol was from Thermo/Fisher (Cat#BP176100, Waltham, MA, USA). Details of other materials and suppliers are provided in the specific sections.
Wang F., Zhang M., Yuan M., Xia Z., Yang F., Zhang S., Lin T., Luo L., Tang J, & Zhang Y. (2023). A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation. British journal of pharmacology, 180(15), 1930-1948.
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2

Comprehensive Protocol for Cell Stress Assays

Check if the same lab product or an alternative is used in the 5 most similar protocols
JNUTS013 (≥98% purity) was synthesized in the Tang laboratory. Lipopolysaccharide (LPS, from Escherichia coli O111:B4) was purchased from Sigma-Aldrich (Cat#L2630, Steinheim, Germany). Dimethyl sulfoxide (DMSO) was purchased from Aladdin Bio-Chem Technology (Cat#67–68-5, Shanghai, China). d-galactosamine (D-galactosamine) was purchased from Sigma-Aldrich (Cat#G1639, Steinheim, Germany). Hydrocortisone (Cat#HY-N0583), curcumin (Cat#HY-N0005), rapamycin (Cat#HY-10219), MG132 (Cat#HY-13259), bortezomib (Cat#HY-10227), hydroxychloroquine (Cat#HY-W031727), leupeptin hemisulfate (Cat#HY-18234A), bafilomycin A1 (Cat#HY-100558), 3-methyladenine (Cat#HY-19312), dextran sulfate sodium salt (DSSS, Cat#HY-116282B) and disuccinimidyl suberate (DSS) (Cat#HY-W019543) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). Phorbol 12-myristate 13-acetate (PMA, Cat#S7791), nigericin sodium salt (Cat#S6653), cycloheximide (Cat#S7418) and Z-VAD-FMK (Cat#S7023) were purchased from Selleckchem (Houston, TX, USA). NP-40 lysis buffer (Cat#K1127) was purchased from Apexbio (Houston, TX, USA). NH4Cl (Cat#A100621) was purchased from Sangon Biotech (Shanghai, China). β-Mercaptoethanol was from Thermo/Fisher (Cat#BP176100, Waltham, MA, USA). Details of other materials and suppliers are provided in the specific sections.
Chiang L.W., Grenier J.M., Ettwiller L., Jenkins L.P., Ficenec D., Martin J., Jin F., DiStefano P.S, & Wood A. (2001). An orchestrated gene expression component of neuronal programmed cell death revealed by cDNA array analysis. Proceedings of the National Academy of Sciences of the United States of America, 98(5), 2814-2819.
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3

Reagents for Cell Signaling Studies

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Lipopolysaccharides (LPS) (L2630) were obtained from Sigma (Sigma-Aldrich, St. Louis, MO). Cycloheximide (S7418), nigericin sodium salt (S6653), and MCC950 sodium salt (S7809) were obtained from Selleck (Houston, TX). Withaferin A (M7490), latrunculin A (M6896), and paclitaxel (M1970) were obtained from Abmole (Houston, TX). Z-YVAD-FMK (ab141388) and phalloidin fluorescein isothiocyanate (FITC) reagent (ab235137) were obtained from Abcam. 7-Actinomycin D (7-AAD, A1310) and disuccinimidyl suberate (DSS) (21655) were obtained from Invitrogen.
He S., Li L., Chen H., Hu X., Wang W., Zhang H., Wei R., Zhang X., Chen Y, & Liu X. (2022). PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation. Journal of Virology, 96(14), e02127-21.
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