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1 0 polydioxanone

Manufactured by Johnson & Johnson
Sourced in United States

1–0 polydioxanone is a synthetic absorbable suture material. It is a monofilament suture made from the polymer polydioxanone. The core function of 1–0 polydioxanone is to provide temporary wound closure and support during the healing process.

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2 protocols using 1 0 polydioxanone

1

Surgical Repair of Achilles Tendon Rupture

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Local anesthetic was administered (20 ml of Marcain® and adrenalin 5 mg/ml, AstraZeneca, London, UK) in the dermis, subcutis and peritendinous space prior to surgery. The patients were then placed in prone position and a medial incision was made through the skin, fascia cruris and paratenon. The rupture was located by the surgeon and a 10 mm Achilles tendon biopsy was taken from the ruptured area, another 10 mm biopsy was taken 3-4 cm away from the rupture side as a control, from a visibly intact tendon area.
A modified Kessler suture with two 1–0 polydioxanone (Ethicon, Somerville, New Jersey, USA) sutures, was used to bring the tendon ends together. The paratenon and fascia cruris were then closed with 3–0 Vicryl (Ethicon, Somerville, New Jersey, USA) and the skin was sutured with 3–0 Ethilon (Ethicon, Somerville, New Jersey, USA). The same anesthetic and surgical techniques were used for all patient using a predefined study protocol.
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2

Surgical Repair of Achilles Tendon Rupture

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The same anesthetic and surgical techniques were used for all patients using a predefined study protocol, as described earlier (14 (link)). Local anesthetic was administered (20 ml of Marcain® and adrenalin 5 mg/ml, AstraZeneca, London, UK) in the dermis, subcutis and peritendinous space prior to surgery. The patients were subsequently placed in the prone position and a medial incision was made through the skin, fascia cruris and paratenon. From the ruptured area, the surgeon retrieved Achilles tendon biopsies. The tendon ends were sutured together using a modified Kessler suture with two 1–0 polydioxanone (Ethicon, Somerville, New Jersey, USA) sutures. The paratenon and fascia cruris were then closed with 3–0 Vicryl (Ethicon, Somerville, New Jersey, USA) and the skin was sutured with 3–0 Ethilon (Ethicon, Somerville, New Jersey, USA).
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