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Imipramine hydrochloride

Manufactured by Fujifilm
Sourced in Japan

Imipramine hydrochloride is a chemical compound used in laboratory equipment. It is a crystalline solid that is soluble in water and organic solvents. The core function of imipramine hydrochloride is as a reference standard in analytical testing and research applications.

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3 protocols using imipramine hydrochloride

1

Analytical Characterization of Imipramine

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Imipramine hydrochloride was obtained from Wako Pure Chemical Industries Ltd. (Osaka, Japan) and sodium chloride was procured from the Sigma Chemical Company (St. Louis, MO, USA). Ethanol, Tween 80, and propylene glycol for pharmaceutical use were locally purchased. All chemicals were of analytical grade. All the reagents used for the LCMS analysis were of LCMS grade.
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2

Analytical Standards for Pharmaceutical Compounds

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Standards of imipramine hydrochloride (Lot no: SKL0836, molecular weight: 316.87 g/mole) and chloroquine diphosphate (Lot no: LEE6907, molecular weight: 515.86 g/mole) were purchased from Fujifilm Wako Pure Chemical Industries (Osaka, Japan). Hematoxylin, eosin, xylene, pathomount, LC-MS grade ultrapure water, and ethanol were also purchased from Fujifilm Wako Pure Chemical Industries (Osaka, Japan). Super cryo-embedding medium (SCEM) and optimum cutting temperature (OCT) compounds were purchased from Waters, Section Lab, and Sakura Finetek Japan, respectively. Matrix α-cyano-4-hydroxycinnamic acid (CHCA) was purchased from Sigma-Aldrich (St. Louis, MO, USA).
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3

Imipramine Hydrochloride Dosing Protocol

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Imipramine hydrochloride (lot no. WDN5600, Wako Pure Chemical Industries, Ltd., Osaka, Japan) was suspended in 0.5% methylcellulose solution (lot no. TWN7021, Wako Pure Chemical Industries, Ltd.) to achieve concentrations of 2 and 20 mg/mL as dosing solutions for Exp 3.
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