Cgp 55845

All chemicals and kynurenic acid were purchased from Sigma-Aldrich (St. Louis, MO, USA). APV, tetrodotoxin (TTX), Stressin-1, CGP 55845 and NBI 35965 were purchased from Tocris/R&D systems (Bristol, UK).

SST was purchased from Bachem. The following chemicals were products of R&D Systems: tetrodotoxin (TTX), kynurenic acid, picrotoxin, CGP55845, BAPTA, SCH23390, linopirdine, ZD7288, CH275, L-803,087, BIM 23052, 1R,1′S,3′R/1R,1′R,3′S)-L-054,264 (abbreviated as L-054,264), octreotide, CYN154806, GDP-β-S, MDL12330A, SQ22536, Rp-cAMPS, H89, KT5720, GF109203X, forskolin, IBMX, HJC0350. PKI(5-24) was provided by Enzo Life Sciences. Drugs were initially prepared in stock solution, aliquoted and stored at −20°C. For those chemicals which are only soluble in dimethyl sulfoxide (DMSO), the concentration of DMSO was less than 0.1%. This concentration of DMSO either in the recording pipettes or in the bath had no significant effects on neuronal activity.