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Philos plate

Manufactured by DePuy
Sourced in Switzerland, United States

The PHILOS plate is a surgical implant designed for the fixation of fractures in the proximal humerus. It is made of titanium alloy and features multiple screw holes to allow for secure fixation of the plate to the bone. The PHILOS plate is intended to provide stable fixation and facilitate the healing process in patients with proximal humerus fractures.

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7 protocols using philos plate

1

Bicortical Locking Screw Fixation for Proximal Humerus Fractures

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Under general anesthesia, all the patients underwent surgery in the supine position using the standard deltopectoral approach. The fracture fragments are first temporarily reduced with Kirschner wires, and then sutures are passed through the rotator cuff tendon and fixed with a proximal humeral internal locking system (PHILOS) plate (DePuy Synthes, Zuchwil, Switzerland) with one 3.5-mm cortical screw and two or three BCL screws (Fig. 1). After the PHILOS plate fixation, the 3.5-mm cortical screw is loosened from the longitudinal combi-hole of the plate shaft. The rotator cuff tendons are then attached with four to five No. 5 non-absorbable braided sutures (Ethibond, Somerville, NJ, USA). The sutures are then passed through the 3.5-mm cortical screw and tied off. Finally, the cortical screw is fastened fully to complete the procedure.

Simple radiographs of the conventional bicortical locking screw fixation. a Preoperative, b Postoperative and c 3 months after surgery

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2

Operative Approach for Humeral Fractures

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The operative approach was deltopectoral or deltoid-split, depending on the fracture characteristics. Autologous bone graft was harvested from the iliac crest in a standard manner. Fractures were fixed with a PHILOS plate (DePuy Synthes, Zuchwil, Switzerland), using at least four locking screws in the humeral head with lengths assessed per the Spross protocol [25 (link)].
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3

Titanium Plate Fixation for Proximal Humerus Fractures

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The PHILOS plate (DePuy Synthes®) is made of titanium alloy. The shaft was fixed with three 3.5-mm screws in all cases. The number of 3.5-mm humeral head screws used ranged from 5 to 9 (on average, 7). An average of three cannulated humeral head screws (range, 2–5) were augmented with 0.5–1 ml of trauma cement (PMMA). The lengths of the humeral head screws were selected so that their tips extended to the subchondral surface of the humeral head without penetration of the articular surface. The surgeries were performed according to the manufacturer’s instructions and guidelines via the deltopectoral approach by five different orthopedic surgeons, all familiar with PHF treatment. If the fracture involved the bicipial groove, an epiosseous soft-tissue tenodesis of the long head of the biceps tendon was performed. The arm was put in a sling for comfort only for the first week postoperatively. Free passive and active range of motion was allowed immediately after surgery without weight-bearing for 6 weeks.
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4

Surgical Technique for Proximal Humerus Fractures

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Sixteen well-trained orthopedic surgeons performed all the operations. We placed patients in a “beach chair” position on an operating table under general anesthesia. The fracture site was exposed using the deltopectoral approach. Nonabsorbable sutures were passed through the junction of the tuberosities and rotator cuff to promote mobilization and reduce tuberosities. An adequate fibular strut was inserted into the intramedullary canal through the fracture site and medialized toward the calcar to reduce the column in patients with a comminuted medial hinge or severe osteoporosis. Subsequently, the humeral head and shaft were reduced. Once reduction was confirmed with a C-arm X-ray machine after temporary fixation, the plate (Philos plate; DePuy Synthes, Oberdorf, Switzerland; 3.5 mm LCP proximal humerus plate, IRENE, Tianjin, China) was fixed with screws. Final confirmatory orthogonal X-rays were used to show the position of the plates and screws and fracture reduction. We used No.2 Ethibond sutures to fix the tuberosities, which passed through the junction of the rotator cuff and the tuberosities. Additional supplementary tuberosity screws were used, if necessary. After testing for shoulder activity, the wound was closed.
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5

Shoulder Activity in Proximal Humerus Fracture

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This multi-centric prospective study investigated shoulder activity with accelerometer-based trackers during the first six postoperative weeks in elderly patients with a complex proximal humerus fracture treated with the PHILOS plate (DePuy Synthes, Zuchwil, Switzerland). The two study centers were the University Hospitals Leuven and Medical University Innsbruck. Note that the study sites will be referred to in an anonymized manner below. The study was approved by the local ethical committees (approval numbers S62376 and 1281/2018, respectively).
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6

Long-term Outcomes of Proximal Humerus Fractures

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The final data set comprised 58 patients (male: 26, female: 32) with a mean age of 55.6 ± 14.4 years (range: 17.7 to 101.3 years, age at surgery). All patients were followed up at least six years (7.9 ± 1.4 (range: 6.2 to 11.1 years) after surgical intervention. According to the Neer classification [13 (link)], the cohort consisted of 24 2-part fractures, 25 3-part fractures, and 9 4-part fractures. According to the AO/OTA classification [14 ], these fractures were classified as 24 A, 22 B, and 12 C fractures. All fractures were treated with an angular stable plate (PHILOS® plate, DePuy Synthes, West Chester, Pennsylvania, USA or Non-Contact Bridging plate, Zimmer, Germany GmbH, Freiburg, Deutschland, or 4.5-mm T-plate (Stratec Medical, Oberdorf, Schweiz).
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7

Proximal Humerus Fracture Treatment Outcomes

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The final data set comprised 90 patients (male: 12, female: 78; height: 164.8 ± 7.2 cm; weight: 68.9 ± 17.8 kg) with a mean age of 78.1 ± 5.2 years (range 70.1 to 89.8 years). According to the Neer classification [20 (link)], the cohort consisted of 34 2-part fractures, 41 3-part fractures, and 12 4-part fractures. According to the AO/OTA classification [21 ], these fractures were classified as 34 A, 32 B, and 21 C fractures. No traumatic nerve injury or vascular comorbidities occurred. Fractures were treated in 28.9% of the cases with a PHILOS® plate (DePuy Synthes, West Chester, Pennsylvania, USA) and in 71.1% of the cases with a WINSTA-PH WS proximal Humerus (Axomed GmbH, Freiburg, Germany).
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