Modular swa

Manufactured by Roche

Sourced in Switzerland, United States

The Modular SWA is a laboratory equipment product offered by Roche. It is a modular system designed for specific laboratory applications. The core function of the Modular SWA is to provide a flexible and customizable solution for various laboratory tasks.

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Lab products found in correlation

Agilent 1100, by Agilent Technologies (1 mentions) Monovette tube, by Sarstedt (1 mentions)

Close spelling variants of this product

Modular SWA P800 analyzer (4 citations) Modular Analytics SWA (4 citations) Modular SWA P300 (1 citations)

4 protocols using modular swa

Serum Biomarker Measurement for Cancer

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Blood was collected in Sarstedt Monovette Serum Z tubes (Sarstedt Ltd, Leicester, UK) and allowed to coagulate for 30 minutes before centrifugation at 800 × g for 10 min. The serum fraction was aliquotted into cryotubes and stored at -80°C. CA19-9 levels were measured using ELISA (Human Pancreatic & GI Cancer ELISA Kit, Alpha Diagnostics International, San Antonio, Tx, USA). Pre-operative total serum bilirubin (μmol/L) (Roche Modular SWA) was measured in the hospital Clinical Biochemistry Department.

Shaw V.E., Lane B., Jenkinson C., Cox T., Greenhalf W., Halloran C.M., Tang J., Sutton R., Neoptolemos J.P, & Costello E. (2014). Serum cytokine biomarker panels for discriminating pancreatic cancer from benign pancreatic disease. Molecular Cancer, 13, 114.

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Plasma Metanephrines Analysis Protocol

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Plasma-fractioned metanephrines (metanephrine and normetanephrine) were quantified by liquid chromatography with electrochemical detection (Agilent 1100; Agilent Technologies, Wilmington, DE, USA) in the Laboratory for Endocrinology and Metabolism at the 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague [41 (link)].
Blood biochemistry, including sodium, potassium, urea, creatinine, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, and plasma glucose, was analyzed using a multianalyzer (Modular SWA; Roche Diagnostics, Basel, Switzerland) in the Institute of Medical Biochemistry and Laboratory Diagnostics of the General University Hospital and 1st Faculty of Medicine, Charles University in Prague. Creatinine clearance was calculated using the Cockcroft–Gault equation.

Kvasnička J., Zelinka T., Petrák O., Rosa J., Štrauch B., Krátká Z., Indra T., Markvartová A., Widimský J J.r, & Holaj R. (2019). Catecholamines Induce Left Ventricular Subclinical Systolic Dysfunction: A Speckle-Tracking Echocardiography Study. Cancers, 11(3), 318.

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Analysis of Plasma Catecholamines and Biochemistry

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Plasma catecholamines were analysed by HPLC with a fluorometric detector (HPLC/FLD 1100S, Agilent Technologies Inc.). The system was calibrated with a catecholamine standard using the ClinRep test kit (Recipe Chemicals and Instruments GmbH, Munich, Germany). Plasma-fractioned metanephrine (metanephrine and normetanephrine) was quantified by liquid chromatography with electrochemical detection (HPLC/ED 1100, Agilent Technologies Inc.) in the Laboratory for Endocrinology and Metabolism at the Third Department of Medicine, General University Hospital and First Faculty of Medicine, Charles University in Prague (24 (link)). Blood biochemistry, including sodium, potassium, urea, creatinine, total cholesterol, LDL, HDL, triglycerides and plasma glucose, was analysed using a multi-analyser (Modular SWA; Roche Diagnostics) in the Institute of Medical Biochemistry and Laboratory Diagnostics of the General University Hospital and First Faculty of Medicine, Charles University in Prague with international accreditation. Creatinine clearance was determined during 24 h of urine collection.

Kvasnička J., Petrák O., Zelinka T., Klímová J., Kološov B., Novák K., Michalský D., Widimský J J.r, & Holaj R. (2021). Effect of adrenalectomy on remission of subclinical left ventricular dysfunction in patients with pheochromocytoma: a speckle-tracking echocardiography study. Endocrine Connections, 10(12), 1538-1549.

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UKCTOCS Blood Sample Processing Protocol

Cited 1 time

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UKCTOCS blood samples were collected and processed throughout the trial according to a standardised SOP (8 (link), 13 (link)). Blood was taken in Greiner gel tubes (8 mL separation tubes; Greiner Bio-one 455071, Stonehouse UK) at one of 13 trial centres, transported overnight at ambient temperature to a central laboratory, centrifuged at 4,000 rpm for 10 minutes and serum aliquoted and stored in liquid nitrogen. All UKCTOCS blood samples used in this study were processed within 20 hours of venepuncture. PBRU blood samples were collected in Sarstedt Monovette tubes (Sarstedt Ltd, Leicester, UK), placed at 4 °C for 15 min and centrifuged at 800 ×g for 10 min at 4°C. Serum was stored in aliquots at − 80 °C. Preoperative total serum bilirubin (μmol/L) (Roche Modular SWA) and CA19–9 levels were measured in hospital Clinical Biochemistry Departments, or by CA19-9 ELISA (Human Pancreatic & GI Cancer ELISA Kit, Alpha Diagnostics International, San Antonio, Texas, USA).

Jenkinson C., Elliott V.L., Evans A., Oldfield L., Jenkins R.E., O’Brien D.P., Apostolidou S., Gentry-Maharaj A., Fourkala E.O., Jacobs I.J., Menon U., Cox T., Campbell F., Pereira S.P., Tuveson D.A., Park B.K., Greenhalf W., Sutton R., Timms J.F., Neoptolemos J.P, & Costello E. (2015). Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clinical cancer research : an official journal of the American Association for Cancer Research, 22(7), 1734-1743.

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