All subjects underwent a comprehensive ophthalmic evaluation, including assessment of distance best-corrected visual acuity (BCVA) using Snellen charts and converted to LogMAR for statistical evaluation, Goldmann applanation tonometry, slit lamp biomicroscopy, dilated fundus examination, multicolor imaging, and spectral-domain structural OCT with enhanced depth imaging (EDI) (Heidelberg Spectralis HR2 + OCT; Heidelberg Engineering, Heidelberg, Germany) of the macular and peripapillary area. FA and ICGA using the Heidelberg Spectralis OCT system (HRA2 + OCT; Heidelberg Engineering) and/or Swept Source OCT-angiography (SS-OCT-A) using the PLEXElite 9000 system (Carl Zeiss, Meditec Inc., Dublin, CA, USA) were performed to detect the presence of macular neovascularization (MNV) at baseline.
Hra2 oct
Manufactured by Heidelberg Engineering
Sourced in United States
The HRA2 + OCT; is a multi-functional imaging device that combines Heidelberg Retina Angiography (HRA2) and Optical Coherence Tomography (OCT) technologies. It provides high-resolution imaging of the retina and choroid without the need for dye injection.
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Lab products found in correlation
2 protocols using hra2 oct
1
Comprehensive Ophthalmic Evaluation for Macular Neovascularization
2
Multimodal Imaging for Macular Conditions
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Spectral-domain optical coherence tomography (SD-OCT, HRA2 + OCT, Heidelberg Engineering, Heidelberg, Germany) was acquired with a minimum acquisition protocol of 20- × 15-degree pattern centered on the fovea constituting of 19 OCT B-scans. FAF and Multicolor® were acquired simultaneously with the same instrumentation. Color fundus photograph (CFP) was obtained with either Clarus 500 (Carl Zeiss Meditec, Version 01 05/2017) or Topcon TRC-50DX (Topcon fundus camera, Tokyo, Japan). FA, ICGA, and/or OCTA were obtained to exclude the presence of any MNV subtypes. OCTA was achieved using either RTVue XR (RTVue XR Avanti, Optovue, Inc., Fremont, CA) equipped with the AngioVue software (version 2017.1.0.151; Optovue Inc) or Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). A 3- × 3-mm or 6- × 6-mm volumetric scan pattern was considered with projection artifact removal. The signal strength cut-off was set ≥ 45 signal strength index (SSI) for RTVue and > 15 Q score for Spectralis OCT.
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