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11 mercapto 1 undecanol hs ch2 11oh

Manufactured by Merck Group

11-Mercapto-1-undecanol (HS(CH2)11OH) is a chemical compound with the molecular formula C11H24OS. It consists of an 11-carbon linear alkyl chain with a sulfhydryl (-SH) group at one end and a hydroxyl (-OH) group at the other end.

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2 protocols using 11 mercapto 1 undecanol hs ch2 11oh

1

Biotin-Amyloid Binding Assay Protocol

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Hexafluoro-2-propanol (HFIP) was purchased from Sigma-Aldrich (catalog number 105228-25G, St. Louis, MO). Dimethyl sulfoxide (DMSO) was purchased from Fisher Scientific (catalog number D12345, Pittsburgh, PA). Biotin-PEG-SH was purchased from Nanocs Inc. (catalog number PG2-BNTH-5k, New York, NY). 11-Mercapto-1-undecanol (HS(CH2)11OH) was obtained from Sigma Aldrich, St. Louis, MO (catalog number 447528-1G). The thiols were used as received. Streptavidin was purchased from Thermo Scientific (catalog number 43-4301, Pittsburgh, PA). Biotin was purchased from Sigma Aldrich (catalog number B4501-500MG) St. Louis, MO). β-amyloid peptide (1-40) (Seq: DAEFRHDSGYEVHHQKLVFFAEDV GS NKGAIIGLMVGGVV) and Biotin labeled β-amyloid peptide (1-40) (Seq: Biotin-DAEFRHDSGY EVHHQKLVFFAEDVGSNKGAIIGLMVGGVV) were purchased from EZBiolab Inc., Carmel, IN. Spin-labeled fluorene HO-4160 (SLF) was synthesized as described in16 (link).
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2

Functionalization of Gold Surfaces

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Gold-coated silicon surfaces of ~ 1 × 1 cm were first washed with ethanol, dried with a gentle flow of nitrogen, and cleaned for 15 min by UV-O3 treatment. Surfaces were then immersed overnight in an ethanol solution containing a 1 mM mixture (1:99 mol/mol) of 16-mercaptohexadodecanoic acid (HS(CH2)16COOH) (Sigma-Aldrich) and 11-mercapto-1-undecanol (HS(CH2)11OH; Sigma-Aldrich).
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